Protein Alignment CG12069 and Akt2

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_031460.1
• Gene: Akt2 / 11652
• MGIID: 104874
• Length: 481
• Species: Mus musculus
• Alignment Length: 304
• Identity: 111/304 - (36%)
• Similarity: 178/304 - (58%)
• Gaps: 5/304 - (1%)

  Fly    34 ATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNV 98
            |.|.......::|::....||.|:||||.||||:.:|.|||.|.|.|:.|:...:|:|.::|..|
Mouse   139 AVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203

  Fly    99 LRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHH 163
            |::...|....|..:::..|.|..|:....|||||.:..:.|.|||.:||||.|::..||||||.
Mouse   204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS 268

  Fly   164 CSLLYRDLKPENIMMDKNGYLKVTDFGFAKK--VETRTM-TLCGTPEYLPPEIIQSKPYGTSVDW 225
            ..::|||:|.||:|:||:|::|:||||..|:  .:..|| |.|||||||.||:::...||.:|||
Mouse   269 RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDW 333

  Fly   226 WAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNL 290
            |..||:::|.:.|..||  :|:|...::..|...:.:.|.......:.|:..||:.|..:|.|..
Mouse   334 WGLGVVMYEMMCGRLPF--YNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGG 396

  Fly   291 INGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFD 334
            .:..:::.||.:|..:.|..::.:.:..|:.|.:::..|...||
Mouse   397 PSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFD 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	109/293 (37%)
Akt2	NP_031460.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	108/287 (38%)