Protein Alignment CG12069 and prkg2

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_002934043.3
• Gene: prkg2 / 100497736
• XenbaseID: XB-GENE-951552
• Length: 787
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 122/312 - (39%)
• Similarity: 178/312 - (57%)
• Gaps: 7/312 - (2%)

  Fly    28 DFNKKFATNTPSPSTG-LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSH 91
            :.||...|....||.. .::.||..|||.|.||:|:||:.:...:.:|.|.:.|..||..:|..|
 Frog   458 ELNKMKQTLARFPSASPFENLEIVTTLGVGGFGRVELVKVKNENLVFALKCIKKRHIVDNRQQEH 522

  Fly    92 VMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFL 156
            :.||||:|.....|..|.|..::||...:|::|....||||::..|....|.|..|:|....|..
 Frog   523 IHSEKNILEEACSPFIVKLYCTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTAKFCTGCVTE 587

  Fly   157 ALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV--ETRTMTLCGTPEYLPPEIIQSKPY 219
            |.||||...:|||||||||:::|..||:|:.|||||||:  ..:|.|.||||||:.||:|.:|.:
 Frog   588 AFEYLHQKGVLYRDLKPENLLLDSEGYVKLVDFGFAKKIFPGQKTWTFCGTPEYVAPEVILNKGH 652

  Fly   220 GTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALR--HLVDHLLQVD 282
            ..|||:|:.|:|::|.:.|..||:  ..|.|.:||.|.:...|:..|.:...|  .|:..|.:.:
 Frog   653 SFSVDFWSLGILLYELLTGSPPFT--GPDQMIIYNLILQGIEKIEFYKNITKRPEDLIRRLCREN 715

  Fly   283 LSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFD 334
            .::|.||:.||..|||:|.||....|..|..:::.:|..|.:..|.|.|.||
 Frog   716 PAERLGNMKNGIADIKKHRWFNGFNWEGLNTRSLPSPLKPELEGPTDHSYFD 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	117/294 (40%)
prkg2	XP_002934043.3	CAP_ED	194..303	CDD:237999
		CAP_ED	312..427	CDD:237999
		STKc_cGK	484..743	CDD:270724	106/260 (41%)