Protein Alignment CG12069 and prkg1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_002935474.2
• Gene: prkg1 / 100494278
• XenbaseID: XB-GENE-966465
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 333
• Identity: 127/333 - (38%)
• Similarity: 186/333 - (55%)
• Gaps: 13/333 - (3%)

  Fly    21 ILDKLREDFNKKFATNTPSPSTG---LDDYEIKATLGSGSFGKVQLVR-ERESGVYYASKQLSKD 81
            :.:|..||...|......:...|   |.|:.|..|||.|.||:|:||: :.:....:|.|.|.|.
 Frog   345 VSNKAYEDAEAKAKYEAEAAFFGNLKLADFNIIDTLGVGGFGRVELVQLKSDECKTFAMKILKKR 409

  Fly    82 QIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQ 146
            .||.|:|..|:.|||.:::|......|.|..::||...||:::....||||:|..|....|.:..
 Frog   410 HIVDTRQQEHIRSEKQIMQSAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFDDST 474

  Fly   147 ARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV--ETRTMTLCGTPEYL 209
            .|||.|.|..|..|||...::||||||||:::|..||.|:.|||||||:  ..:|.|.||||||:
 Frog   475 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYV 539

  Fly   210 PPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEA--DYKMPSYFSGALR 272
            .||||.:|.:..|.|:|:.|:|::|.:.|..|||  ..|.|..||.|...  ..:.|...:....
 Frog   540 APEIILNKGHDISADYWSLGILMYELLTGSPPFS--GPDPMKTYNIILRGIDMIEFPKKITKNAA 602

  Fly   273 HLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDKV- 336
            :|:..|.:.:.|:|.|||.||.:||::|:||:...|..|...|:..|.:|::::|.|.||||..
 Frog   603 NLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFP 667

  Fly   337 --SDKPRP 342
              ::.|.|
 Frog   668 EDNEDPPP 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	118/294 (40%)
prkg1	XP_002935474.2	DD_cGKI-beta	4..55	CDD:213375
		CAP_ED	117..226	CDD:237999
		CAP_ED	236..340	CDD:237999
		STKc_cGK	380..640	CDD:270724	106/261 (41%)
		S_TK_X	635..>678	CDD:214529	13/41 (32%)