Protein Alignment CG12069 and pkn2

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_004913783.1
• Gene: pkn2 / 100488854
• XenbaseID: XB-GENE-995298
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 328
• Identity: 118/328 - (35%)
• Similarity: 177/328 - (53%)
• Gaps: 19/328 - (5%)

  Fly    44 LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNV---LRSMTFP 105
            |.|:...|.||.|.||||.|...:.:...:|.|.|.|..||...:|..:|.||.:   :.|:..|
 Frog   652 LQDFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHP 716

  Fly   106 NTVNLIASYKDFDSLYLVLPLIGGGELFTY-HRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYR 169
            ..|||.|.::..|.:..|:....||:|..: |..|  |:|.:|.||||.|.|.|:|||...::||
 Frog   717 FLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDV--FSEPRAVFYAACVVLGLQYLHEHKIVYR 779

  Fly   170 DLKPENIMMDKNGYLKVTDFGFAKK---VETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVL 231
            |||.:|:::|..|::|:.|||..|:   ...||.|.|||||:|.||::....|..:||||..|||
 Frog   780 DLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVL 844

  Fly   232 VFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRD 296
            ::|.:.|.|||...:.:  .:::.|...:.:.|.:.|.....::..||:.:..:|.|.......|
 Frog   845 IYEMLVGESPFPGDDEE--EVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAED 907

  Fly   297 IKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDK--VSDKP------RPKAKTMRHEEAF 353
            :|:|.:|:..:|..||.:.|..|:||.|...||:||||.  .|:.|      .|:..|...:|||
 Frog   908 VKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQEAF 972

  Fly   354 ADF 356
            .||
 Frog   973 RDF 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	107/296 (36%)
pkn2	XP_004913783.1	HR1_PKN_1	40..105	CDD:212012
		HR1	129..197	CDD:469609
		HR1	208..281	CDD:469609
		C2_PKN-like	390..471	CDD:176069
		STKc_PKN	655..980	CDD:270741	116/325 (36%)