Protein Alignment Spn100A and SERPINA7

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 76/338 - (22%)
• Similarity: 137/338 - (40%)
• Gaps: 57/338 - (16%)

  Fly   313 EKLAKIMAAPALTAGEPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVSRVNGARSLFQQ 377
            :|..::....||..|:..|   ||.|..|.|||         :...|......|.::.|:
Human   123 KKELELQIGNALFIGKHLK---PLAKFLNDVKT---------LYETEVFSTDFSNISAAK----- 170

  Fly   378 DDITSALSANSITGRSAG------SKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDAVK 436
            .:|.|.:...: .|:..|      ..:.|:|.|.::::..|||||...:......|.:.....|:
Human   171 QEINSHVEMQT-KGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQ 234

  Fly   437 APMMHARGK-FQVADLPQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFLLAKKQF 500
            .||||...: :.:.|: ::...||.:.|..:..|| .|||.|.: :..|.:.:.:.......:..
Human   235 VPMMHQMEQYYHLVDM-ELNCTVLQMDYSKNALAL-FVLPKEGQ-MESVEAAMSSKTLKKWNRLL 296

  Fly   501 QMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVD----------EIV 555
            |...:.:.:|||.:..|....|.|.:||::..:|. .|..|.|:||..:.:.          :..
Human   297 QKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSE-NADFSGLTEDNGLKLSNRPAGFVLPTQAA 360

  Fly   556 QFVNVRVDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPEL--PGVERFEVNRPFAYFIVDCQ 618
            ....:.:.|.|:.|         |..|.||.:    .:||...  |.:   :::|.|...|::..
Human   361 HKAVLHIGEKGTEA---------AAVPEVELS----DQPENTFLHPII---QIDRSFMLLILERS 409

  Fly   619 EQFVLASGKIYTP 631
            .:.:|..||:..|
Human   410 TRSILFLGKVVNP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815
		serpin	<380..627	CDD:381000	58/265 (22%)
SERPINA7	XP_006724746.1	serpinA7_TBG	37..425	CDD:381023	76/338 (22%)