Protein Alignment Spn100A and Serpina12

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 306
• Identity: 73/306 - (23%)
• Similarity: 130/306 - (42%)
• Gaps: 40/306 - (13%)

  Fly   330 EKVRLPLQKLENAVKTAAKDGADEIML---ALESHLPSVSRVNGARSLFQQDDITSALSANSITG 391
            :|:| |.|:..|..|...  .||.::.   .||:....::|....::..:..::..::...::
Mouse   142 QKLR-PQQRFLNLAKNVY--DADMVLTNFQDLENTQKDINRYISQKTHSRIKNMVKSIDPGTV-- 201

  Fly   392 RSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDAVKAPMMHARGKFQVADLPQVKA 456
                    |:|.|.:|:||.|...| ..:...:|.||:.....||.|||..||.:.:|...|:..
Mouse   202 --------MILTNYIYFRGRWQYEF-DPKQTKEEEFFIEKGKTVKVPMMFQRGLYDMAYDSQLSC 257

  Fly   457 RVLSLPYETSRYALCIVLPDETEGLSDVISQ-LQTSDFLLAKKQFQMKELHISMPKFQVEETSRS 520
            .:|.:||. .......||||  .|...::.| ||...|...|.....:.:.:.:||.::..|...
Mouse   258 TILEIPYR-GNITATFVLPD--NGKLKLLEQGLQADIFAKWKSLLSKRVVDVWVPKLRISSTYNM 319

  Fly   521 EAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQFVNVRVDEGGSSANSLSAATMQARTPSVE 585
            :.:|.::|:.|:|.. ...|:.:|....:.|.|.|....:::||.|..    .||...|:|
Mouse   320 KKVLSRLGISKIFEE-NGDLTRISSHRSLKVGEAVHKAELKMDEKGME----GAAGSGAQT---- 375

  Fly   586 STVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQFVLASGKIYTP 631
               ||:..|       ...:::|||...|.:.....::...:||.|
Mouse   376 ---LPMETP-------RHMKLDRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815
		serpin	<380..627	CDD:381000	59/247 (24%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	72/304 (24%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		8/35 (23%)