Protein Alignment Spn100A and serpinb1

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001011419.1
• Gene: serpinb1 / 496899
• XenbaseID: XB-GENE-1217264
• Length: 377
• Species: Xenopus tropicalis
• Alignment Length: 353
• Identity: 89/353 - (25%)
• Similarity: 148/353 - (41%)
• Gaps: 59/353 - (16%)

  Fly   300 IKNLEENETVQEEEKLAKIMAAPALTA-----GEPEKVRLP-----LQKLENA------VKTAAK 348
            :|:|..|......|...|.:::.||..     ||.....||     ::|..||      ..:||:
 Frog    63 VKDLHSNFQTLNAEINKKNVSSYALNLANRLFGEKSFKFLPDFLSSVKKQYNADLGTVDFISAAE 127

  Fly   349 DGADEIMLALESHLPSVSRVNGARSLFQQDDITSALSANSITGRSAGSKSKMLLFNGLYYRGSWA 413
            |...||              |...|...:..|...|||.::     .|.:|::|.|.:|::|.||
 Frog   128 DARKEI--------------NTWVSEQTKGKIPEVLSAGAV-----NSFTKLVLVNAIYFKGDWA 173

  Fly   414 NPFYQLRDGSDEFFFMTNEDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLP--- 475
            ..| :.....|..|.:..::.....||:...|.....:|::..|||.|||.....::.||||
 Frog   174 KKF-KAEHTKDMPFQLNKKEQKTVKMMYQMEKLPFNYIPEINCRVLELPYVDYELSMVIVLPDNI 237

  Fly   476 -DETEGLSDVISQLQTSDFLLAKKQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQ 539
             |:|.||..:..:|.........:.....::|:.:|||::|::.:.::.|..||:..:|....|.
 Frog   238 NDDTTGLQQLEKELSLEKINEWTENMMPIDVHVHLPKFKLEDSYKLKSQLAGMGMADLFEAGSAD 302

  Fly   540 LSLLSEDPDVHVDEIVQFVNVRVDEGGSSANSLSAA-TMQARTPSVESTVLPVPEPEPELPGVER 603
            ||.:|...|:::.|::....|.|:|.|:.|.:.||. .|..                  |...|.
 Frog   303 LSGMSGSNDLYLSEVIHKSFVEVNEEGTEAAAASAGIAMMC------------------LMREEE 349

  Fly   604 FEVNRPFAYFIVDCQEQFVLASGKIYTP 631
            |..|.||.:||.....:.:|..|:..:|
 Frog   350 FNANHPFLFFIRHNATKSILFFGRYSSP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815
		serpin	<380..627	CDD:381000	66/251 (26%)
serpinb1	NP_001011419.1	serpinB1_LEI	1..377	CDD:381028	88/351 (25%)