Protein Alignment Spn100A and serpine2

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_073778914.1
• Gene: serpine2 / 393153
• ZFINID: ZDB-GENE-040426-848
• Length: 403
• Species: Danio rerio
• Alignment Length: 614
• Identity: 110/614 - (17%)
• Similarity: 201/614 - (32%)
• Gaps: 246/614 - (40%)

  Fly     6 CAIFVTLLAAIGQGLPTQLEDENHGSFAGQVSQLIALQLLKFNKDIDANQVHSPLGVASILAMLA 70
            |.:.:.||.::.   .:|.:..::|:....:...:.:|:|:  .....|.:.||.||||:|.||.
Zfish     7 CGVLLFLLCSVS---VSQSQSSSYGARGSDLGLQVFMQVLQ--DRAQENVLLSPHGVASVLGMLL 66

  Fly    71 EASEGDTYSEFEQVFGYPKDRTKLRDAYKRILGSYQNRDAAVALPSFQTWLYIYRNNSAREEFKD 135
            ..:.|||             |.:|.:..|                        |:.|.   .:|.
Zfish    67 PGAHGDT-------------RRQLLNGLK------------------------YKKNG---PYKM 91

  Fly   136 LLEKHYYVDVKDISRQEYDWNEPNTSLQLSEEKDNTDSTEGSTEQSNSKDVIGFETLKRIKLDDE 200
            |.:.|                                  :..|.:||: |::....
Zfish    92 LRKLH----------------------------------KSLTTKSNA-DIVTIAN--------- 112

  Fly   201 DIPAIPSDGYGQEIIDKEASKFDRDVDDKQYVEKPVAQAEAELLQKEQKQQATTESEL-ESQPEE 264
              ...|::|:.                                 .||....|..|:.| ||.
Zfish   113 --ALFPNEGFS---------------------------------MKEDFLSANRENFLCESH--- 139

  Fly   265 TTTLSVEKQEKPDMAAEENPAEKQQNKRSDQEESQIKNLEENETVQEEEKLAKIMAAPALTAGEP 329
                ||:..: |:.||
Zfish   140 ----SVDYSD-PEAAA------------------------------------------------- 150

  Fly   330 EKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVSRVNGARSLFQQDDITSALSANSITGRSA 394
                   |.:.:.||.:.|           ..:|||              :|:.:...::|
Zfish   151 -------QSINDWVKNSTK-----------GQIPSV--------------VTADMFDTALT---- 179

  Fly   395 GSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDAVKAPMMHARGKFQV--ADLPQ-VKA 456
                :::..|.::::|.|.:.| |.:......|...:.:..|.|||.....|.:  |..|. .|.
Zfish   180 ----RLVAVNSIFFKGLWKSRF-QPQSTKPRSFTAGDGNTYKVPMMSQLSVFNMGQASTPDGQKY 239

  Fly   457 RVLSLPYETSRYALCIVLP-DETEGLSDVISQLQTSDFLLAKKQFQMKELHISMPKFQVEETSRS 520
            .|:.|||..:..::.|.|| :::..||.::..:.|:......|....:.:.:.||||.||:....
Zfish   240 IVIELPYHGNSMSMFIALPTEDSTPLSSILPHISTNTIQSWTKLMNPRRMRLLMPKFTVEQELDL 304

  Fly   521 EAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQFVNVRVDEGGSSANSLSAATMQARTPSVE 585
            |..||.:|:|.:|.:.:|....||.: .::|.:.:|...:.|:|.|:.|::.::..:.||:..
Zfish   305 ETPLKALGIKDIFDQNKADFRHLSSE-SIYVSKALQKAKIEVNEDGTKASATTSVILHARSSP-- 366

  Fly   586 STVLPVPEPEPELPGVERFEVNRPFAYFI 614
                         |.|   .|:|||.:.|
Zfish   367 -------------PWV---TVDRPFLFLI 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	23/104 (22%)
		serpin	<380..627	CDD:381000	57/239 (24%)
serpine2	XP_073778914.1	None