Protein Alignment Spn100A and serpind1

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_878300.1
• Gene: serpind1 / 359841
• ZFINID: ZDB-GENE-030711-2
• Length: 507
• Species: Danio rerio
• Alignment Length: 572
• Identity: 116/572 - (20%)
• Similarity: 202/572 - (35%)
• Gaps: 147/572 - (25%)

  Fly   126 NNSAREEFKDL------LEKHYYVDVKDISRQEYDWNEPNT---SLQLSEEKDNT---DSTEGST 178
            |:.|....|||      |||...||.:.:|.     ...||   |:.|...::||   |..||..
Zfish    14 NSPALAGVKDLSSHFSTLEKEKTVDARGLSP-----GGENTDMESIPLDFHRENTVTNDLPEGQD 73

  Fly   179 EQSNSKDVIGFETLKRIKLDDEDIPAIPSDGYGQEIIDKEASKFD---RDVDDK----------- 229
            ::    |.:.|:.:    |.::|.    |:|...:.|...|...|   ...|.|
Zfish    74 DE----DYVDFDKI----LGEDDY----SEGDHIDEISTPAPDLDLFYEPSDPKIRRARLLRLFH 126

  Fly   230 -----QYVEKPVAQAEAELLQKEQKQQATTESELESQPEETTTLSVEKQEKPDMAAEENPAEKQQ 289
                 |.:....|:....|.:|.:.:...|::.|.:....:..:.:       |.....|..::|
Zfish   127 GQTRLQRINVVNARFGFRLYRKLRNRLNQTDNILLAPVGISIAMGM-------MGLGVGPNTQEQ 184

  Fly   290 -----------NKRSDQEESQIKNLEENET-------------------VQEEEKLAKIMAAPAL 324
                       |..:..:.|.:..|....|                   |:...::.....|.|.
Zfish   185 LFQTVGFAEFVNASNHYDNSTVHKLFRKLTHRLFRRNFGYTLRSVNDLYVKRNVQIQDSFRADAK 249

  Fly   325 T--AGEPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVSRVNGARSLFQQDDITSALSAN 387
            |  ..||:.|                |.||...|.            .|....|:  ||..|...
Zfish   250 TYYFAEPQSV----------------DFADPAFLV------------KANQRIQK--ITKGLIKE 284

  Fly   388 SITGRSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNE-DAVKAPMMHARGKFQVADL 451
            .:  :|......::|.|.||::|:|...|  .::.:....|..|| ..|:..||..:|.:..|..
Zfish   285 PL--KSVDPNMAVMLLNYLYFKGTWEQKF--PKELTHHRQFRVNEKKQVRVLMMQNKGSYLAAAD 345

  Fly   452 PQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFLLAKKQFQM--KELHISMPKFQV 514
            .::...:|.||| ....::.|.:|.:..|:..:  :.:.|..|:.|....|  :...:..|:|::
Zfish   346 HELNCDILQLPY-AGNISMLIAVPQKLSGMRSL--EQEISPTLVNKWLSNMTNRTREVVFPRFKL 407

  Fly   515 EETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQFVNVRVDEGGSSANSLSAATMQA 579
            |:.......||:||:..:|:.......:.||  .|.::......::.|:|.|:.|   :|.|...
Zfish   408 EQNYDLIEHLKEMGMTDIFTEKGDFSPMTSE--KVIINWFKHQGSITVNEEGTEA---AAMTHIG 467

  Fly   580 RTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQFVLASGKIYTP 631
            ..|....|               ||.|:|||.:.|.:.:...|:..|::..|
Zfish   468 FMPLSTQT---------------RFIVDRPFLFLIYEHRTGCVVFMGRVVDP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	10/25 (40%)
		serpin	<380..627	CDD:381000	57/249 (23%)
serpind1	NP_878300.1	serpinD1_HCF2	50..507	CDD:381004	103/531 (19%)