Protein Alignment Spn100A and serpina1

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001071226.1
• Gene: serpina1 / 322701
• ZFINID: ZDB-GENE-030131-1421
• Length: 429
• Species: Danio rerio
• Alignment Length: 349
• Identity: 83/349 - (23%)
• Similarity: 148/349 - (42%)
• Gaps: 64/349 - (18%)

  Fly   315 LAKIMAAPALTAGEPEKVR-------------LPLQKLENAVKTAAKDGADEIMLALESHLPSVS 366
            |::|.:....:|..||:|.             ....:||.....|.:||    ...::..|....
Zfish   111 LSQIYSGLGYSALTPEQVNEGYEHLLHMLGHSQDAMQLEAGAGVAIRDG----FKVVDQFLKDAQ 171

  Fly   367 RVNGARSL---FQQDDITSALSANSITGRSAGSK-----------SKMLLFNGLYYRGSWANPF- 416
            ....:.:.   |.:.:|.:| ..|....|....|           :.|:|.|.:|:||.|..||
Zfish   172 HYYNSEAFGVDFSKPEIAAA-EINKFIARKTHDKITNMVKDLDADTVMMLINYMYFRGKWEKPFD 235

  Fly   417 YQLRDGSDEFFFMTNEDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLPDETEGL 481
            .:|...:|  |.:..:..|:..||...|::.:...|..:..|:.:||: ...::.|||||:.:
Zfish   236 AKLTHKAD--FKVDQDTTVQVDMMKRTGRYDIYQDPVNQTTVMMVPYK-GNTSMMIVLPDDGK-- 295

  Fly   482 SDVISQLQTSDFLLAKKQFQMK----ELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSL 542
               :.:|:.|......|.:..|    .:.:.||||.:..||:.:.:||.||:...|: .:|..|.
Zfish   296 ---MKELEESICRHHLKNWHDKLFRSSVDLFMPKFSISATSKLDGILKDMGMTDAFN-DKADFSG 356

  Fly   543 LSEDPDVHVDEIVQFVNVRVDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPELPGVERFEVN 607
            ::|:..|.|.:::....:.|||.|:.|.:::  |::....|:..||:                :|
Zfish   357 MTEEVKVKVSQVLHQAVMSVDEKGTEAAAIT--TIEIMPMSLPDTVI----------------LN 403

  Fly   608 RPFAYFIVDCQEQFVLASGKIYTP 631
            |||...||:.....:|..|||..|
Zfish   404 RPFLVLIVEDSTMSILFMGKITNP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815
		serpin	<380..627	CDD:381000	66/262 (25%)
serpina1	NP_001071226.1	serpinA_A1AT-like	65..429	CDD:381017	83/349 (24%)