Protein Alignment Spn100A and Serpina3n

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_033278.2
• Gene: Serpina3n / 20716
• MGIID: 105045
• Length: 418
• Species: Mus musculus
• Alignment Length: 662
• Identity: 119/662 - (17%)
• Similarity: 194/662 - (29%)
• Gaps: 292/662 - (44%)

  Fly     3 AVLCAIFVTLLAAIGQGLPTQLEDENHGSFAGQVSQLIALQLLKFNKDI-------------DAN 54
            ||||....||    |.....| ||.::|      :||.:|.|...|.|.             |.|
Mouse    17 AVLCFPDGTL----GMDAAVQ-EDHDNG------TQLDSLTLASINTDFAFSLYKELVLKNPDKN 70

  Fly    55 QVHSPLGVASILAMLAEASEGDTYSEFEQVFGYPKDRTKLRDAYKRILGSYQNRDAAVALPSFQT 119
            .|.|||.:::.||:::..::|:|..|..:...:....|...|.:
Mouse    71 IVFSPLSISAALAVMSLGAKGNTLEEILEGLKFNLTETSEADIH--------------------- 114

  Fly   120 WLYIYRNNSAREEFKDLLEKHYYVDVKDISRQEYDWNEPNTSLQLSEEKDNTDSTEGSTEQSNSK 184
                       :.|..||::                        |::.||....:.||.
Mouse   115 -----------QGFGHLLQR------------------------LNQPKDQVQISTGSA------ 138

  Fly   185 DVIGFETLKRIKLDDEDIPAIPSDGYGQEIIDKEASKFDRDVDDKQYVEKPVAQAEAELLQKEQK 249
                                                         .::||              :
Mouse   139 ---------------------------------------------LFIEK--------------R 144

  Fly   250 QQATTESELESQPEETTTLSVEKQEKPDMAAEENPAEKQQNKRSDQEESQIKNLEENETVQEEEK 314
            ||..||.                                                       :||
Mouse   145 QQILTEF-------------------------------------------------------QEK 154

  Fly   315 LAKIMAAPALTAG--EPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVSRVNGARSLFQQ 377
            ...:..|.|.||.  :|.:.:   :.:.:.|:...:....|::..|:
Mouse   155 ARALYQAEAFTADFQQPRQAK---KLINDYVRKQTQGMIKELVSDLD------------------ 198

  Fly   378 DDITSALSANSITGRSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDAVKAPMMHA 442
                              .::.|:|.|.:|::..|..||..|.....||:
Mouse   199 ------------------KRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFY--------------- 230

  Fly   443 RGKFQVADLPQVKARVLSLPYETSRYALC--------------IVLPDETEGLSDVISQLQTSDF 493
            .||.:...:|.:....|:.||.......|              .:|||:.: :..|.:.||....
Mouse   231 AGKRRPVIVPMMSMEDLTTPYFRDEELFCTVVELKYTGNASAMFILPDQGK-MQQVEASLQPETL 294

  Fly   494 LLAK---KQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIV 555
            ...|   |...:.|||  :|||.:......|.:|.::|:::||| |:|.||.::...|:.|.::|
Mouse   295 RKWKNSLKPRMIDELH--LPKFSISTDYSLEDVLSKLGIREVFS-TQADLSAITGTKDLRVSQVV 356

  Fly   556 QFVNVRVDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQ 620
            ....:.|.|.|:.|   :|||          .|..||......|....|  ||||...|.|.:.:
Mouse   357 HKAVLDVAETGTEA---AAAT----------GVKFVPMSAKLYPLTVYF--NRPFLIMIFDTETE 406

  Fly   621 FVLASGKIYTPE 632
            ......||..|:
Mouse   407 IAPFIAKIANPK 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	20/117 (17%)
		serpin	<380..627	CDD:381000	62/263 (24%)
Serpina3n	NP_033278.2	serpinA3_A1AC	37..418	CDD:381019	108/635 (17%)
		RCL	367..392		9/37 (24%)