Protein Alignment Spn100A and Serpina10

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_598301.2
• Gene: Serpina10 / 171154
• RGDID: 621220
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 107/504 - (21%)
• Similarity: 189/504 - (37%)
• Gaps: 125/504 - (24%)

  Fly   144 DVKDISRQEYDWNEPNTSLQLSEEKDNTDSTEGSTEQSNSKDVIGFETLKRIKLDDEDIPAIPSD 208
            |.::.:.:||:|.:|        ..||......|.:.||.....||..|::|.:..:
  Rat    39 DYENQTWEEYEWADP--------RDDNEYWLRASQQLSNETSSFGFSLLRKISMRHD-------- 87

  Fly   209 GYGQEIIDKEASKFDRDVDDKQYVEKPVAQAEAELLQKEQKQQATTESELESQPEETTTLSVEKQ 273
              |..|.    |.|...|            |...|:       ...:.|.:.|.|....|....|
  Rat    88 --GNVIF----SPFGLSV------------AMVNLM-------LGAKGETKVQVENGLNLQALSQ 127

  Fly   274 EKPDMAAEENPAEKQQNKRSDQEESQIKNLEENETVQEEEKLAKIMAAPALTAG---------EP 329
            ..|.:.    ||..::.|               ||....:||       .||.|         |.
  Rat   128 AGPLIL----PALFKRVK---------------ETFSSNKKL-------GLTQGSFAFIHKDFEI 166

  Fly   330 EKVRLPLQKL---ENAVKTAAKDGADEIMLALESHLPSVSRVNGARSLFQQDDITSALSANSITG 391
            :|....|..:   ...|.|..::.:.  ...|.:|..:.........||  |:|
  Rat   167 KKTYFNLSTMYFDTEYVPTNFRNSSQ--ARGLMNHYINKETEGKIPKLF--DEI----------- 216

  Fly   392 RSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDAVKAPMMHARGKFQVADLPQVKA 456
               ..::|::|.:.:.::|.|..||..:...:|. |.:....|||.|||:..|.|......:.:.
  Rat   217 ---NPETKLILVDYILFKGKWLTPFDPIFTEADT-FHLDKYKAVKVPMMYREGNFASTFDKKFRC 277

  Fly   457 RVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFL-LAKKQFQMKELHISMPKFQVEETSRS 520
            .:|.|||:.:...|.:::  |..|....:....|:|.: :..:..:.:::.:..|||::.:....
  Rat   278 HILKLPYQGNATMLVVLM--EKSGDHLALEDYLTTDLVEMWLQDMKTRKMEVFFPKFKLNQRYEM 340

  Fly   521 EAMLKQMGLKKVFSRTEAQLSLLSE-DPDVHVDEIVQFVNVRVDEGGSS--ANSLSAATMQARTP 582
            ..:|||:|::::|| |.|.||.||. ..::.|.::||...:.|||.|:.  :.::|..|.....|
  Rat   341 HELLKQVGIRRIFS-TSADLSELSAVARNLQVSKVVQQSVLEVDERGTEVVSGTVSEITAYCMPP 404

  Fly   583 SVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQFVLASGKIYTP 631
            .:                    :|:|||.:.|.:...|.:|..|::..|
  Rat   405 VI--------------------KVDRPFHFIIYEEMSQMLLFLGRVVNP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	1/1 (100%)
		serpin	<380..627	CDD:381000	58/250 (23%)
Serpina10	NP_598301.2	serpinA10_PZI	56..434	CDD:381011	102/479 (21%)
		Heparin-binding. /evidence=ECO:0000250	128..145		6/35 (17%)