Protein Alignment Spn100A and LOC1281803

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_321764.6
• Gene: LOC1281803 / 1281803
• VectorBaseID: AGAMI1_006118
• Length: 586
• Species: Anopheles gambiae
• Alignment Length: 670
• Identity: 225/670 - (33%)
• Similarity: 336/670 - (50%)
• Gaps: 127/670 - (18%)

  Fly     4 VLCAIFVTLLAAIGQGLPTQLEDENHG---SFAGQVSQLIALQLLKFNKDIDANQVHSPLGVASI 65
            ::||:...:..|. ..||.|....:.|   |..|..:.:|...|||...:...|.|.||:|.:||
Mosquito    10 LVCALLAVVTPAC-NALPKQRYSRDGGEPRSLVGVSTNIITSSLLKGAAETPGNHVFSPIGFSSI 73

  Fly    66 LAMLAEASEGDTYSEFEQVFGYPKDRTKLRDAY----KRILGSYQNRDAAVALPSFQTWLYIYRN 126
            |||::|.:||.|..|...||.:|.||..:|.|:    ||:.|.....:     |.|:||.|||:|
Mosquito    74 LAMISEGAEGQTLKELYDVFKFPTDRDLVRKAFDVSLKRLSGQNPTDE-----PQFKTWFYIYKN 133

  Fly   127 NSAREEFKDLLEKHYYVDVKDISRQEYDWNEPNTSL-------QLSEEKDNTDS----TEGSTEQ 180
            ||..:.:||:||::|.|:|:||.|.:|:::||.|||       ::.||.:..|.    .|..:..
Mosquito   134 NSVLQAYKDVLEQNYAVEVRDIERNDYNFDEPKTSLDPVVVEEEIIEESNGPDGDNLVLEQGSNN 198

  Fly   181 SNSKDVIGFETLK---RIKLDDEDIPAIPSD-GYGQEI--IDKEASKFDRDVDDKQYVEKPVAQA 239
            |||||::.||.||   .:.::||    :.:| |...:.  ||.|..|||:::|||:||:....:.
Mosquito   199 SNSKDIVDFEVLKIKSALPVEDE----LRTDTGISTKYDEIDDENPKFDKNIDDKEYVDPTKIKE 259

  Fly   240 EAELLQKEQKQQATTESELESQPEETTTLSVEKQEKPDMAAEENPAEKQQNKRSDQEESQIKNLE 304
            |....:.|...:...:::|:....:.|..|::                    |.|.|
Mosquito   260 ELAKKKMEAMNEVAADADLDDAKMKKTPDSID--------------------RVDHE-------- 296

  Fly   305 ENETVQEEEKLAKIMAAPALTAGEPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVSRVN 369
                                   :|||:.|.|:||       ..|...|:|.|:||. .|..:.|
Mosquito   297 -----------------------QPEKMSLSLKKL-------GLDDEQEVMQAVESQ-GSRRKFN 330

  Fly   370 GARSLFQQDDITSALSANSITGRSAGSK--------SKMLLFNGLYYRGSWANPFYQLRDGSDEF 426
            ..|| |...||.||||.||:.||.|..|        ||||||||||||||||.||.|||....:|
Mosquito   331 VRRS-FLTGDIASALSGNSLVGRKANLKDDEEQVNESKMLLFNGLYYRGSWATPFQQLRTEESKF 394

  Fly   427 FFMTNEDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTS 491
            |  ||.|.....||.::|.|.|....|:.|:.|.|||..|||:|.:::|:..:||.::|......
Mosquito   395 F--TNTDERPVMMMRSQGTFGVGKDEQLDAKFLELPYNNSRYSLLLMVPNNKDGLKELIKNFNPD 457

  Fly   492 DFLLAKKQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQ 556
            .....:|......:.|.:|||:::.|||:|..|.::||..:|: ::|.||.::.:..:||||:||
Mosquito   458 TLSTVQKSLVQMPVQICIPKFRIDTTSRAEKPLAKLGLITMFT-SKADLSGITTEQKIHVDELVQ 521

  Fly   557 FVNVRVDEGGSSANSLSAAT-MQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQ 620
            .|::|||||.||.|:|||.. ::|:|...|.               |:|..::||.:|:.|..:.
Mosquito   522 HVSIRVDEGSSSENALSATNIVEAKTIDDEQ---------------EQFTADKPFLFFVRDVVDD 571

  Fly   621 FVLASGKIYTPEFKEDLPSV 640
            .|:.:|||      .|:|.|
Mosquito   572 IVIVAGKI------TDIPYV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	44/108 (41%)
		serpin	<380..627	CDD:381000	100/255 (39%)
LOC1281803	XP_321764.6	None