Protein Alignment Spn100A and LOC1270171

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_308847.5
• Gene: LOC1270171 / 1270171
• VectorBaseID: AGAMI1_007387
• Length: 859
• Species: Anopheles gambiae
• Alignment Length: 900
• Identity: 181/900 - (20%)
• Similarity: 308/900 - (34%)
• Gaps: 319/900 - (35%)

  Fly     3 AVLCAIFVTLLAAIGQGLPTQLEDENH-GSFAGQ--VSQLIALQLLKFNKDIDANQVHSPLGVAS 64
            :|.|...:.||.:||...|.:.....| .||..:  ....:|.::.:..   |:|.|.||..:..
Mosquito     8 SVRCYAVLMLLISIGTVQPFRRHHPRHQPSFVSRSDFDWNLAREVFRHE---DSNVVFSPFSIKL 69

  Fly    65 ILAMLAEASE--GDTYSEFEQVFGYPKDRTKLRDAYKRILGSYQNRDAAVALPSFQTWLYIYRNN 127
            :|.:|.||:|  ..|.|:.|.....| |..:.|..|.:.|.:.|..:..... ...|.:::   :
Mosquito    70 LLTLLYEAAEPGSGTRSQLEAALVDP-DLNQTRAFYTQFLDASQQTNGDYEF-DIGTKMFL---D 129

  Fly   128 SAR----EEFKDLLEKHYYVDVKDIS--------RQEYDWNEPNTSLQLSE--EKDN-------- 170
            .||    :.:.||||:.|...|:.:|        .:...|.|..|..:::|  .:|.
Mosquito   130 KARAKLPQAYTDLLEQMYRTSVERVSFNGTKATAERINTWCEKVTRGRITELVTEDTLQDAQLVL 194

  Fly   171 ---------------TDSTEGSTEQSNSKDVIGFETLKRIKLDD--------EDIPAIP------ 206
                           .|.|...|......|.:..|.::::.|.|        .::..:|
Mosquito   195 ANVLFLKASWKNSFPDDQTHNRTFHVADGDTVTTEFMRQMDLYDYTVHEQLGAEVLRLPYKGRQF 259

  Fly   207 ----------------SDGYGQEIIDKEASKF----------------------------DRDV- 226
                            :|.....::|..|.:|                            .|||
Mosquito   260 SMNMVLPHRNVSLAALADALTPTMLDSIAEQFVREEVTVLIPKFRFNYGTLLNEAIQRLGIRDVF 324

  Fly   227 -------------DDKQ-------YVEKPVAQAEAELLQKEQKQQATTESEL------ESQP--- 262
                         |.||       .|.|.:.:|..|:.:|.....|.||.:|      :.:|
Mosquito   325 TKNAALPLLASADDAKQSTIKNEVQVSKMLQKAGIEINEKGTLAFAATEIQLVNKFGYDGEPIVF 389

  Fly   263 ------------EETTT-LSVEKQEKPD------MAAEE-------------------------- 282
                        |||.. |.|.|...|.      .||:.
Mosquito   390 EANRPFLFYILDEETNAILFVGKVTDPSRSTPTPRAADRLSVNVGRSFELDEMGIFHGRRWAAVL 454

  Fly   283 ----------NPAEKQQNK------------RSDQEESQIKNL---------------------- 303
                      .|....||:            ..|.:.|.||.:
Mosquito   455 CCVFALTIAATPRRFLQNRFTVDYEPFAGPWNDDFDWSVIKEVLHKAPGNAVISPLSVKALLALL 519

  Fly   304 -----EENETVQEEEKLAKIMAAPALTAGEPEKV--------RLPLQKLENAVKTAAKDGADEIM 355
                 ..:||.:|.::        ||:.|..:.|        :...|:.:|.:.|........:.
Mosquito   520 YEGSASRSETERELQQ--------ALSGGNSQAVPKLQDDLLQYKQQQQQNLLITDRIFYDTTVT 576

  Fly   356 LALESHLPSVSRVNG-ARSLFQQDDITSALSANSITGRSAGSK------------SKMLLFNGLY 407
            |..:.|....:|.|. .:|:..||..::|...|:...::...|            :.|:|.|.:|
Mosquito   577 LLQKYHSIIAARYNATTQSVDFQDTQSAAAEINAWIAQNTRGKIQSIIKPDLLQDALMMLINTIY 641

  Fly   408 YRGSWANPFYQLRDGSDEFFFMTNEDAVKAPM----MHARGK----------------FQVADLP 452
            ::|||:.|            |.||. .|:.|.    ||..|:                |......
Mosquito   642 FKGSWSIP------------FPTNA-TVERPFFTGRMHTAGRYGGPRSVPFMKQRERIFYYKHAE 693

  Fly   453 QVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFL---LAKKQFQMKELHISMPKFQV 514
            |:.|:.|.|||::::.::.:|||||...|..::|:| |:|.:   ||  ....:|:.|.:|:|.:
Mosquito   694 QLGAQFLRLPYDSNQLSMIVVLPDEQVSLGQLLSRL-TADAVHETLA--DMSEEEVEIELPRFSM 755

  Fly   515 EETSRSEAMLKQMGLKKVFSRTEAQLSLLS--EDPDVHVDEIVQFVNVRVDEGGSSANSLSAATM 577
            ..:|.....|:|:|:.:||: .:|:|.|:|  ....:.|..|:|...:.|||.|:.|::.:..|:
Mosquito   756 TYSSSLRECLQQLGVSRVFT-DQAELPLISRGRTTPLKVSTILQKSCILVDEQGTEASAATEGTL 819

  Fly   578 QARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQFVLASGKIYTPE 632
                   ..|:|..|         .:|..||||.:.|.|..:...|.:||:..|:
Mosquito   820 -------VFTILNQP---------VKFIANRPFLFLIYDEGKGNWLFAGKVEDPQ 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	28/110 (25%)
		serpin	<380..627	CDD:381000	72/283 (25%)
LOC1270171	XP_308847.5	None