Protein Alignment Spn100A and Serping1

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_033906.2
• Gene: Serping1 / 12258
• MGIID: 894696
• Length: 504
• Species: Mus musculus
• Alignment Length: 530
• Identity: 110/530 - (20%)
• Similarity: 189/530 - (35%)
• Gaps: 144/530 - (27%)

  Fly   155 WNEPNTSLQLSEEKDNTDSTEGSTEQSNSKDVIGFETLKRIKLDDEDIPA--IPSDGYGQEIIDK 217
            |  |.||:.::...|........:...:|:                  ||  :|:|..||..::.
Mouse    64 W--PTTSVAITITNDTMGKVANESFSQHSQ------------------PAAQLPTDSPGQPPLNS 108

  Fly   218 E-----ASKFDRDVDDKQYVEKPVAQAEAELLQKEQKQQATTESELESQPEETTTLSVE------ 271
            .     ||........:.:..:|:||.       ....:.::|::|.   |..|..||:
Mouse   109 SSQPSTASDLPTQATTEPFCPEPLAQC-------SDSDRDSSEAKLS---EALTDFSVKLYHAFS 163

  Fly   272 --KQEKPDMAAEENPAEKQQNKRSDQEESQIKNLEENETVQEEEKLAKIMAAPALTAGEPEKVRL 334
              |..|.:||.  :|.                            .:|.::....|.||:..|..|
Mouse   164 ATKMAKTNMAF--SPF----------------------------SIASLLTQVLLGAGDSTKSNL 198

  Fly   335 --------PLQKLENAVKTAAKDGADEIMLALESHLPSV----SRVNGARSLFQQ-------DDI 380
                    ....:..|:|..:..|...:....  |.|.:    :.||.::||:..       |..
Mouse   199 ESILSYPKDFACVHQALKGFSSKGVTSVSQIF--HSPDLAIRDTYVNASQSLYGSSPRVLGPDSA 261

  Fly   381 TSALSANSITGRSAGSKSK-----------MLLFNGLYYRGSWANPFYQLRDGSDEFFFMTNEDA 434
            .:....|:....:...|.:           ::|.|.:|....|...| :.:.....||:  ....
Mouse   262 ANLELINTWVAENTNHKIRKLLDSLPSDTCLVLLNAVYLSAKWKITF-EPKKMMAPFFY--KNSM 323

  Fly   435 VKAPMMHARGKFQVA--DLPQVKARV--LSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFLL 495
            :|.||| :..|:.||  |...:||:|  |.|.:..|...:..|.|...  |.||...|..:.|..
Mouse   324 IKVPMM-SSVKYPVAQFDDHTLKAKVGQLQLSHNLSFVIVVPVFPKHQ--LKDVEKALNPTVFKA 385

  Fly   496 AKKQFQMKEL---HISMPKFQVEETSRSEAMLKQMGLKKVFSRT-EAQLSLLSEDPDVHVDEIVQ 556
            ..|:.::.:.   :::||..:|:.   |:.||..|...:.|..| :..|..|:||||:.|..:..
Mouse   386 IMKKLELSKFLPTYLTMPHIKVKS---SQDMLSVMEKLEFFDFTYDLNLCGLTEDPDLQVSAMKH 447

  Fly   557 FVNVRVDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQF 621
            ...:.:.|.|..|.:.||.:.        ...||:            |||.|||.:.:.|.|.:|
Mouse   448 ETVLELTESGVEAAAASAISF--------GRSLPI------------FEVQRPFLFLLWDQQHRF 492

  Fly   622 VLASGKIYTP 631
            .:..|::|.|
Mouse   493 PVFMGRVYDP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815
		serpin	<380..627	CDD:381000	63/265 (24%)
Serping1	NP_033906.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..67		2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..141		12/80 (15%)
		serpinG1_C1-INH	141..500	CDD:381006	91/422 (22%)