Protein Alignment Spn100A and serpinb4

DIOPT Version :10

• Sequence 1: NP_651818.1
• Gene: Spn100A / 43642
• FlyBaseID: FBgn0039795
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_002936465.2
• Gene: serpinb4 / 100490314
• XenbaseID: XB-GENE-5787878
• Length: 392
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 125/595 - (21%)
• Similarity: 210/595 - (35%)
• Gaps: 229/595 - (38%)

  Fly    45 LKFNKDIDANQVHSPLGVASILAMLAEASEGDTYSEFEQVFGYPKDRTKLRDAYKRILGSYQNRD 109
            ||.|.: ..|.:.|||.:.|.:.::...|:|||.:|.|:||.:|           ...||..::
 Frog    19 LKKNPE-KKNILFSPLSICSAMGLVLLGSKGDTAAEIEKVFHFP-----------AAAGSRSSK- 70

  Fly   110 AAVALPSFQTWLYIYRNNSAREE-----FKDLLEKHYYVDVKDISRQEYDWNEPNTSLQLSEEKD 169
                 ||.|       ..:.:.:     ||||
 Frog    71 -----PSCQ-------QQTCQAQGVHLLFKDL--------------------------------- 90

  Fly   170 NTDSTEGSTEQSNSKDVIGFETLKRIKLDDEDIPAIPSDGYGQEIIDKEASKFDRDVDDKQYVEK 234
                               |.||.:           |:|.|            :..:.::.|.||
 Frog    91 -------------------FSTLNK-----------PNDHY------------ELSIANRAYGEK 113

  Fly   235 PVAQAEAELLQKEQKQQATTESELESQPEETTTLSVEKQEKPDMAAEENPAEKQQNKRSDQEESQ 299
            ....:|..||..||...||.|             ||:.:.|.|...:                 |
 Frog   114 SFPFSEQYLLCIEQLYNATLE-------------SVDFKTKADDVIQ-----------------Q 148

  Fly   300 IKNLEENETVQEEEKLAKIMAAPALTAGEPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPS 364
            |....|::|   :.|:..:.|..:|
 Frog   149 INAWVESKT---KGKIQNLFAKGSL---------------------------------------- 170

  Fly   365 VSRVNGARSLFQQDDITSALSANSITGRSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFM 429
                          |.|:||:                |.|.:|::|||...| :..:.:|..||:
 Frog   171 --------------DSTTALA----------------LVNAVYFKGSWKKQF-KKENTTDAPFFL 204

  Fly   430 TNEDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDF- 493
            ...|.....||..:||:::...|::|.|:|.||||.. :::.|:|||:.:||:::.:.|....|
 Frog   205 NKNDKTSVKMMSQKGKYKLGSNPELKCRILKLPYEEG-FSMKIILPDDIDGLAELETHLTYETFT 268

  Fly   494 -LLAKKQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQF 557
             |:..::.:..::.:.:|:|:..||.....:|:.||:...|.  .|.||.:|:...:.:..:|..
 Frog   269 KLMDLQRTREVQVVVKLPQFKFGETYSLTEVLQSMGMTSAFH--GANLSGISDKAGLAISTVVHK 331

  Fly   558 VNVRVDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVDCQEQFV 622
            ..:.|:|.|:.|   :|||      .:..||...|.|..|      |.|:|||.:.|.....:.:
 Frog   332 SYIEVNEEGTEA---AAAT------GIGITVTSAPLPPQE------FIVDRPFLFCIEHISTKSL 381

  Fly   623 LASGKIYTPE 632
            |..|:...||
 Frog   382 LFYGRFTFPE 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn100A	NP_651818.1	serpin	41..>146	CDD:476815	26/105 (25%)
		serpin	<380..627	CDD:381000	67/248 (27%)
serpinb4	XP_002936465.2	serpinB	10..387	CDD:381072	123/589 (21%)