DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and P4H2

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_566279.1	Gene:	P4H2 / 819804	AraportID:	AT3G06300	Length:	299	Species:	Arabidopsis thaliana

Alignment Length:	227	Identity:	74/227 - (32%)
Similarity:	113/227 - (49%)	Gaps:	28/227 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 CLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEV 369
            ||   .:||..|:.|.|::.|...|...:|...|:..|...|..:|...|:|:.|....:|.::|
plant    24 CL---ISSPSSIINPSKVKQVSSKPRAFVYEGFLTDLECDHLISLAKENLQRSAVADNDNGESQV 85

  Fly   370 VKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFF-NKTNSN 433
            ...|||...:...|.:|:...:..::|..|.......|.||::.|..|..||.|:|:| :|.|
plant    86 SDVRTSSGTFISKGKDPIVSGIEDKLSTWTFLPKENGEDLQVLRYEHGQKYDAHFDYFHDKVN-- 148

  Fly   434 MTAMSGDRIATVLFYLTDVEQGGATVFPNIRK---------------------AVFPQRGSVVMW 477
             .|..|.||||||.||::|.:||.||||:.::                     ||.|::|:.:::
plant   149 -IARGGHRIATVLLYLSNVTKGGETVFPDAQEFSRRSLSENKDDLSDCAKKGIAVKPKKGNALLF 212

  Fly   478 YNLKDNGQIDTQTLHAACPVIVGSKWVCNKWI 509
            :||:.:...|..:||..||||.|.||...|||
plant   213 FNLQQDAIPDPFSLHGGCPVIEGEKWSATKWI 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528
		TPR_11	179..250	CDD:290150
		TPR repeat	179..213	CDD:276809
		TPR repeat	218..248	CDD:276809
		P4Hc	339..510	CDD:214780	63/193 (33%)
P4H2	NP_566279.1	P4Hc	55..245	CDD:214780	63/193 (33%)
P4H2	NP_566279.1	ShKT	259..299	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920