DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	257	Identity:	73/257 - (28%)
Similarity:	122/257 - (47%)	Gaps:	40/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 TGVPTAYQIGCRGQ----------FPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYH 335
            ||.|:..  |.|||          :....|::|           |.:..:|.|:|...|.:::.|
plant    39 TGFPSLR--GLRGQNTRYLRDVSRWANDKDAEL-----------LRIGNVKPEVVSWSPRIIVLH 90

  Fly   336 DVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVKTRTSKVAWFP--DGYNPLTVRLNARISDM 398
            |.|||:|.:.|:.:|.|.|:.:||....:|:......|||...:..  :...|:...:..||:..
plant    91 DFLSPEECEYLKAIARPRLQVSTVVDVKTGKGVKSDVRTSSGMFLTHVERSYPIIQAIEKRIAVF 155

  Fly   399 TGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFP-- 461
            :.......|::|::.|.....|..|:|:|..|.:  ....|.|:||:|.||||..:||.|.||
plant   156 SQVPAENGELIQVLRYEPQQFYKPHHDYFADTFN--LKRGGQRVATMLMYLTDDVEGGETYFPLA 218

  Fly   462 ---------NIRK--AVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIRER 512
                     .|.|  :|.|.:|..|:::::..:||.|.:::|..|.|:.|.||...||:|::
plant   219 GDGDCTCGGKIMKGISVKPTKGDAVLFWSMGLDGQSDPRSIHGGCEVLSGEKWSATKWMRQK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528
		TPR_11	179..250	CDD:290150
		TPR repeat	179..213	CDD:276809
		TPR repeat	218..248	CDD:276809
		P4Hc	339..510	CDD:214780	55/185 (30%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	61/203 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920