Protein Alignment PH4alphaPV and p4ha3

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_073779537.1
• Gene: p4ha3 / 563281
• ZFINID: ZDB-GENE-041010-4
• Length: 642
• Species: Danio rerio
• Alignment Length: 554
• Identity: 149/554 - (26%)
• Similarity: 267/554 - (48%)
• Gaps: 83/554 - (14%)

  Fly    15 TYQVLLLLLR---QAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRL 76
            |..::|.||.   ::.||  ..||:..:.:.:..|.:|||:|..|.....::|:.::|..:.:..
Zfish     6 TLFIVLYLLNMPDESFGE--MFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTS 68

  Fly    77 ENDKARSSTEEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQV-ERIQELRE-------HMP 133
            .:|...:...:.::||:.:|.|::|:..:|:       :.|..::. |.|:.|||       .:|
Zfish    69 LHDGIYNEPSDPIANPIAAFKLVKRLKSEWL-------NVVHSTEAEENIKVLREDYRRMESSLP 126

  Fly   134 THTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQ-----YNVSLTVL----DTYAMGQILFDQK 189
            ...|:..|...|.|:|..|.|.|..:..|......     |.:|::.:    |.:.:|::.:|.:
Zfish   127 KLEDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAYDLE 191

  Fly   190 NYLAAASWIYQSVVLME-------------------AFSMAAPLEISKNEVR----------MVY 225
            :|..:..|..::|.|..                   |||....:   ||:::          ...
Zfish   192 DYYHSVLWFEEAVRLFRGTEWSPENEGTLEDALDHLAFSHFKEI---KNQLKTWITSPHRRCFFQ 253

  Fly   226 AETLLKLNQHADALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQAT-----GV-- 283
            |:...|....:.||.:....|..:|.:.::.....:.|.::   ..|.|......|     |:
Zfish   254 ADLNSKTGNISHALSLSRELLLHDPMNRRVHFNVEKYEKLL---NENLPATSSGLTLKRPDGIYL 315

  Fly   284 --PTAYQIGC--RGQFPPSADS-KLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEI 343
              ..||:..|  :|..|...:: .|:|.|....||.|.|.|::.|::.|.||:||:|..::..|.
Zfish   316 RTRNAYEQLCQTKGSQPKHFENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEA 380

  Fly   344 KELQGMATPGLKRATVYQASSGRNE-VVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYG-- 405
            |.::..|.|||:|:.|   :||.|: ..:.|.||.||..:..:.:..:|:.||:.:||.|:..
Zfish   381 KNIRKYAMPGLRRSVV---ASGMNQATAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPY 442

  Fly   406 SEMLQLMNYGLGGHYDQHYDFFNKTNSNMTAM-SGDRIATVLFYLTDVEQGGATVFPNIRKAVFP 469
            :|.||::|||:||||:.|:|.....:|.:..: :|:|:||::.||:.|:.||:|.|.....:|..
Zfish   443 AEYLQVVNYGIGGHYEPHFDHATSDSSPLYRLKTGNRVATIMIYLSPVQAGGSTAFIYANFSVPV 507

  Fly   470 QRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKW 503
            .:.:.:.|:||..|||.:..||||.||||||:||
Zfish   508 VQNAALFWWNLHKNGQGNVDTLHAGCPVIVGNKW 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	32/138 (23%)
		NrfG	179..>256	CDD:443378	17/105 (16%)
		TPR repeat	179..213	CDD:276809	9/52 (17%)
		TPR repeat	218..248	CDD:276809	7/39 (18%)
		P4Hc	339..510	CDD:214780	65/169 (38%)
p4ha3	XP_073779537.1	None