Protein Alignment PH4alphaPV and PH4alphaMP

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 176/524 - (33%)
• Similarity: 278/524 - (53%)
• Gaps: 20/524 - (3%)

  Fly    12 VLLTYQVLLLLLRQAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRL 76
            :||...||.|:|:.........:|.:|:.||.:.|..|:..|::|..|:.:..:.::..|.::|:
  Fly     1 MLLAKCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRV 65

  Fly    77 ENDKARSSTEEYLSNPLNSFSLIRRMNRDWIIWQ-LYMDDPVGISQVERIQELREHM--PTHTDV 138
            |:..|....::||:||:|:|.||:|::.||..:: ....|....:.::.:..|:|::  |:..|.
  Fly    66 EHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDF 130

  Fly   139 EEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQSVV 203
            ..:..||.|:|.||.|.|.|::.|.|||.:|..:::..|.:.:||.|:..::|.....|:.||:.
  Fly   131 VGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQ 195

  Fly   204 LMEAFSMAAPLEISKNEVRMVYAETLLKLNQHADALKVVNIALTDNPHDIKLLLK-KSEIETMIR 267
            |:...|..:  |.:..:......|...::..|..||.:||..|:..|.....||: :.::|.:|.
  Fly   196 LLGEQSYGS--ESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQLEELIT 258

  Fly   268 TGTNNA-------PPVKVQATGVPTAYQIGCRGQFP--PSADSKLYCLYNRTTSPFLILAPLKME 323
            .|..|.       .|.....:.....|:..|||:..  ||....|.|   |.....|..||.|:|
  Fly   259 DGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRNLRC---RLRKSRLGYAPFKLE 320

  Fly   324 LVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQ-ASSGRNEVVKTRTSKVAWFPDGYNPL 387
            .:.|||.:|..|.|:..|:...||..|.|.:||:|||. ..:|.:.....|||:.|.|....|..
  Fly   321 ELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYSRNAA 385

  Fly   388 TVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSNMTA-MSGDRIATVLFYLTD 451
            |..|:..:.|.:|.|:..:|.||:.|||:||||:.|:|.|.:.:..... :.|:|:||.::||.|
  Fly   386 TKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHGNRMATGIYYLAD 450

  Fly   452 VEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIF 516
            ||.||.|.||.:...|.|:|||::.||||..:|..|.:|.||||||:.||||:.|.|||||.|..
  Fly   451 VEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIANVWIRERNQDN 515

  Fly   517 SRPC 520
            .|||
  Fly   516 VRPC 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	40/133 (30%)
		NrfG	179..>256	CDD:443378	18/76 (24%)
		TPR repeat	179..213	CDD:276809	9/33 (27%)
		TPR repeat	218..248	CDD:276809	7/29 (24%)
		P4Hc	339..510	CDD:214780	73/172 (42%)
PH4alphaMP	NP_524594.2	P4Ha_N	24..158	CDD:462433	40/133 (30%)
		P4Hc	336..509	CDD:214780	73/172 (42%)