Protein Alignment PH4alphaPV and PH4alphaEFB

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 559
• Identity: 196/559 - (35%)
• Similarity: 287/559 - (51%)
• Gaps: 62/559 - (11%)

  Fly     3 SSKWLLPVRVLLTYQVLLLLLRQAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTV 67
            ::.|    |::|...:|||:...|.||.  .|::|.|.:||:.|:.||.|||.|....|.||..:
  Fly     2 AADW----RLMLLLGILLLVGGPANGEV--YTALAEMEELLETESVLITNLEGYIRVQEDKLNFL 60

  Fly    68 RRSITSLRLENDKARSSTEEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQVERIQELRE-- 130
            :..:...:.|:..|......|:|||:|::.|.:|:..||...:..|:..||...::.|.:.|.
  Fly    61 KNKMDEYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLL 125

  Fly   131 HMPTHTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAA 195
            ..|:..|:..|..||.|:|.||.|....::.|.|||.||:..::..|.:.:|:..:...:|....
  Fly   126 KFPSDEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTV 190

  Fly   196 SWIYQSVVLM--------EAFSMAAPLEISKNEVRMVYAETLLKLNQHADALKVVNIALTDNPHD 252
            .|:.:::..|        ::|:.|..||        ..|.:..|......||.:.|..|...||.
  Fly   191 LWMNEAMARMLEEPTNHTQSFTKADILE--------YLAFSTYKEGNIESALTMTNELLQLLPHH 247

  Fly   253 IKLLLKK----SEIETMIR-------TGTNNAP----PVKVQATGVPT--------AYQIGCRGQ 294
            .:....|    .||...::       .||:..|    ||   |...|.        ||::.|||:
  Fly   248 ERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPV---AKSDPAIFDMTERRAYEMLCRGE 309

  Fly   295 FPPSADS--KLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRA 357
            ..||...  .|.|.|.....|||.|.|||:|.|..|||:|:|||.:...||..::.||.|..:||
  Fly   310 LKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRA 374

  Fly   358 TVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQ 422
            ||..:.:|..|....|.||.||.....:.:...:..|.:||||.::..:|.||::|||:||||:.
  Fly   375 TVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEP 439

  Fly   423 HYDFFNKTNS------NMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLK 481
            |:||..|...      |:    |:||||||||::||||||||||.::..|:||::|:...|.||.
  Fly   440 HFDFARKEEQRAFEGLNL----GNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLH 500

  Fly   482 DNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPC 520
            .:||.|.:|.||||||:.|:|||.||||.||.|.|.|||
  Fly   501 RDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPC 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	42/132 (32%)
		NrfG	179..>256	CDD:443378	16/84 (19%)
		TPR repeat	179..213	CDD:276809	6/41 (15%)
		TPR repeat	218..248	CDD:276809	6/29 (21%)
		P4Hc	339..510	CDD:214780	79/176 (45%)
PH4alphaEFB	NP_733371.1	P4Ha_N	28..161	CDD:462433	42/132 (32%)
		P4Hc	356..529	CDD:214780	79/176 (45%)