Protein Alignment PH4alphaPV and CG18233

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 170/501 - (33%)
• Similarity: 281/501 - (56%)
• Gaps: 35/501 - (6%)

  Fly    32 HCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPLNSF 96
            :.:||.|:||||.:|.:.:.|...||..|::|:..:...:.:|:..|.|..:..|:::|||||:|
  Fly    31 YSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLNAF 95

  Fly    97 SLIRRMNRDWIIWQLYMDDPVGISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGLKVPEISH 161
            .||||:|:||...|.|...|:|:.|:..:|::....|...|:.|.:.|:.||::||.|:..:|:.
  Fly    96 GLIRRLNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKDIAK 160

  Fly   162 GFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQSVVLMEAFSMAAPLEISKNEVRMV-- 224
            |.|...::|..|...|..|:....|:...:..:..|..:::.|    |....||| .|.::.:
  Fly   161 GLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKL----STDGSLEI-MNRLKEIEL 220

  Fly   225 --YAETLLKLNQHADALKVVNIALTDNPH----DIKLLLKKSEIETMIRTGTNNAPPVKVQATGV 283
              :|..:.|.:.:.....:.|..:.|..:    |.||:..:..|.:.::...|:      .:|..
  Fly   221 KGFATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQLISSELKQWIND------DSTTP 279

  Fly   284 PTAYQIGCRGQFPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQG 348
            ||.:.:||||.||..  |.|.|.||.:|:.||.|||||||.:..|||:|::|:|:|.|:|:|::|
  Fly   280 PTDHNLGCRGLFPKK--SNLVCRYNSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKG 342

  Fly   349 MATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMN 413
            ..|   :....:.:.....|:|    |:|.|... .:..:.|:|.||||||||.|.....:||.|
  Fly   343 EIT---EMENGWTSLGDPKEIV----SRVYWIRK-ESSFSKRINQRISDMTGFKLEEFPAIQLAN 399

  Fly   414 YGLGGHYDQHYDFF----NKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSV 474
            :|:||::..||||:    .:.:.|.|.  ||||.:::||..:|.|||.||||:::.||.|::|:.
  Fly   400 FGVGGYFKPHYDFYTDRLKEVDVNNTL--GDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNA 462

  Fly   475 VMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPC 520
            :.|:|..|:...|.::||:.|||:|||:|...||:....|:|.:||
  Fly   463 LFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPC 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	48/130 (37%)
		NrfG	179..>256	CDD:443378	15/84 (18%)
		TPR repeat	179..213	CDD:276809	5/33 (15%)
		TPR repeat	218..248	CDD:276809	4/33 (12%)
		P4Hc	339..510	CDD:214780	67/174 (39%)
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	47/129 (36%)
		P4Hc	333..498	CDD:214780	67/174 (39%)