DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and CG34041

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	80/349 - (22%)
Similarity:	167/349 - (47%)	Gaps:	43/349 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLTYQVLLLLLRQAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSL--- 74
            :|:..::::.|..:..|..|..|.:.::.:|.::..::..||:|...||.||:|:..::..|
  Fly   238 ILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATY 302

  Fly    75 --RLENDKARSSTEEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQVERIQELREHMPTHTD 137
              :.|.||...:     |:|:.|:|||..|..||..|||::.:..|..::..:..:::::||..|
  Fly   303 HIQFERDKLAIA-----SSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKND 362

  Fly   138 VEEAVTALDRIQSTYGLKVPEISHGFLNGKQ--YNVS-----------------LTVLDTYAMGQ 183
            :.|....:.::.:.|.:...:|::|.:.|.|  |..|                 :::.|..|:..
  Fly   363 ISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSD 427

  Fly   184 ILFDQKNYLAAASWIYQSVVLMEAFSMAAPLEISKNEVRMVYAETLLKLNQHADALKVVNIALTD 248
            ...:.|:|..:..|:..::.::|:.:...|: :...::.:..||..:|......||:.|..||..
  Fly   428 HSMEMKDYNKSKEWLNVAISMLESSAYWDPI-VPSADLYLKLAEVYVKQQNWTLALETVEFALKS 491

  Fly   249 NPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQFPPSADSKLYCLYNRTTSP 313
            ||.:.:|:..:..:...|..|...:|.:.::...    |::...|        .|||.|:.....
  Fly   492 NPRNAQLIRMQKRLSYHILLGPPKSPKLNIENND----YRLRKNG--------SLYCFYDTKIRT 544

  Fly   314 FL-ILAPLKMELVGLDPYMVLYHD 336
            |. :|||:|.|::.:||.::|||:
  Fly   545 FYSLLAPIKAEVLFIDPLVILYHE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	34/133 (26%)
		TPR_11	179..250	CDD:290150	14/70 (20%)
		TPR repeat	179..213	CDD:276809	5/33 (15%)
		TPR repeat	218..248	CDD:276809	8/29 (28%)
		P4Hc	339..510	CDD:214780
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	34/133 (26%)
		TPR repeat	452..491	CDD:276809	9/39 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840