Protein Alignment PH4alphaPV and CG18749

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 186/500 - (37%)
• Similarity: 272/500 - (54%)
• Gaps: 53/500 - (10%)

  Fly    29 EESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPL 93
            ::|:..|...::|||::|.:|:|||:.|...|:.|...:.||:..:..||.:.:|..|.||.|||
  Fly    29 KKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPL 93

  Fly    94 NSFSLIRRMNRDWIIWQLYM----DDPVGISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGL 154
            |||.||.|::..|..|..|.    ::.:|  .:|..:.:|:.:||.:|:::|...:..:...|.|
  Fly    94 NSFRLIHRLHTSWRKWYQYAIKVENNALG--HIENARLMRKMLPTSSDLQQACRGIHDLMYFYDL 156

  Fly   155 KVPEISHGFLNG-KQYNVSLTVLDTYAMGQI-LFDQKNYLAAASWIYQSVVLMEAFSMAAPLEIS 217
            |..|::.|.|.| .|....||..|..|:|:. :.:||:.||.| |...|:...:..       |.
  Fly   157 KPEELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEA-WYNLSLTRFDNI-------IE 213

  Fly   218 KNEVRMVYAETLLKLNQHADALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATG 282
            |.:|...:|..|.|..|..:|.:    ...:.|..|....:....|.::.| |.|...| ||
  Fly   214 KYQVHKAWALLLAKNKQLTEAFQ----HFENKPEGIVASNEVIHFEGVLAT-TQNCTAV-VQ--- 269

  Fly   283 VPTAYQIGCRGQFPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQ 347
                         .||  .||:|.||.:|:||..:||||||.:|||||||::|||:...||..:.
  Fly   270 -------------KPS--KKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGML 319

  Fly   348 GMATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLM 412
            ..:..||..:    .|..::||   ||||.:...|...     ||.|::||||.::..|:...|:
  Fly   320 NSSDFGLSES----VSGLKSEV---RTSKDSHIVDAKT-----LNERVTDMTGLSMEMSDPFSLI 372

  Fly   413 NYGLGGHYDQHYDFFNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMW 477
            |||||||:..|:||...||:. ....|||||||||||.:|:.|||||||.:...|.|::||.|.|
  Fly   373 NYGLGGHFILHHDFHEYTNTT-RLKQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFW 436

  Fly   478 YNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPCLK 522
            |||.::|.::::|||.|||||.|||:|..|||.|..|:|..||:|
  Fly   437 YNLHNSGAVNSKTLHTACPVISGSKYVLTKWINELPQMFVTPCMK 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	45/134 (34%)
		NrfG	179..>256	CDD:443378	19/77 (25%)
		TPR repeat	179..213	CDD:276809	9/34 (26%)
		TPR repeat	218..248	CDD:276809	7/29 (24%)
		P4Hc	339..510	CDD:214780	76/170 (45%)
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	45/134 (34%)
		P4Hc	314..468	CDD:214780	75/166 (45%)