Protein Alignment PH4alphaPV and CG18749

DIOPT Version :9

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 186/500 - (37%)
• Similarity: 272/500 - (54%)
• Gaps: 53/500 - (10%)

  Fly    29 EESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPL 93
            ::|:..|...::|||::|.:|:|||:.|...|:.|...:.||:..:..||.:.:|..|.||.|||
  Fly    29 KKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPL 93

  Fly    94 NSFSLIRRMNRDWIIWQLYM----DDPVGISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGL 154
            |||.||.|::..|..|..|.    ::.:|  .:|..:.:|:.:||.:|:::|...:..:...|.|
  Fly    94 NSFRLIHRLHTSWRKWYQYAIKVENNALG--HIENARLMRKMLPTSSDLQQACRGIHDLMYFYDL 156

  Fly   155 KVPEISHGFLNG-KQYNVSLTVLDTYAMGQI-LFDQKNYLAAASWIYQSVVLMEAFSMAAPLEIS 217
            |..|::.|.|.| .|....||..|..|:|:. :.:||:.||.| |...|:...:..       |.
  Fly   157 KPEELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEA-WYNLSLTRFDNI-------IE 213

  Fly   218 KNEVRMVYAETLLKLNQHADALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATG 282
            |.:|...:|..|.|..|..:|.:    ...:.|..|....:....|.::.| |.|...| ||
  Fly   214 KYQVHKAWALLLAKNKQLTEAFQ----HFENKPEGIVASNEVIHFEGVLAT-TQNCTAV-VQ--- 269

  Fly   283 VPTAYQIGCRGQFPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQ 347
                         .||  .||:|.||.:|:||..:||||||.:|||||||::|||:...||..:.
  Fly   270 -------------KPS--KKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGML 319

  Fly   348 GMATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLM 412
            ..:..||..:    .|..::||   ||||.:...|...     ||.|::||||.::..|:...|:
  Fly   320 NSSDFGLSES----VSGLKSEV---RTSKDSHIVDAKT-----LNERVTDMTGLSMEMSDPFSLI 372

  Fly   413 NYGLGGHYDQHYDFFNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMW 477
            |||||||:..|:||...||:. ....|||||||||||.:|:.|||||||.:...|.|::||.|.|
  Fly   373 NYGLGGHFILHHDFHEYTNTT-RLKQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFW 436

  Fly   478 YNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPCLK 522
            |||.::|.::::|||.|||||.|||:|..|||.|..|:|..||:|
  Fly   437 YNLHNSGAVNSKTLHTACPVISGSKYVLTKWINELPQMFVTPCMK 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	44/132 (33%)
		TPR_11	179..250	CDD:290150	17/71 (24%)
		TPR repeat	179..213	CDD:276809	9/34 (26%)
		TPR repeat	218..248	CDD:276809	7/29 (24%)
		P4Hc	339..510	CDD:214780	76/170 (45%)
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	44/132 (33%)
		P4Hc	314..468	CDD:214780	75/166 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461770
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.890