Protein Alignment PH4alphaPV and PH4alphaNE3

DIOPT Version :9

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 480
• Identity: 174/480 - (36%)
• Similarity: 265/480 - (55%)
• Gaps: 37/480 - (7%)

  Fly    42 LLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPLNSFSLIRRMNRDW 106
            |:.|:.:|||||.:||.::::|...::|....||.....|:...||||.|||:||.|||.|.:||
  Fly    27 LMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEYLGNPLHSFPLIRHMYQDW 91

  Fly   107 IIWQLYMDDPVGISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNV 171
            ...:.:|..|||..:::.::.....:|...|.|||..::.||..|||:...::::|.::..::|.
  Fly    92 RYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYGMMPWDMANGLIDNVRFNS 156

  Fly   172 SLTVLDTYAMGQILFDQKNYLAAASWIYQSVVLM-EAFS-MAAPLEISKNEVRMVYAETLLKLNQ 234
            :|..||.:.:.::.|....:..|..||..|...| |.:| :...|.:::.:|.::.|..|::|::
  Fly   157 TLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEYSGVYEVLGMNRQDVALLQARCLVELDR 221

  Fly   235 HADALKVVNIALTDNP----HDIKLL--LKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRG 293
            ..:|.:|    |.|.|    :.|.||  .|.:..|.:     :::|.       :...|:..||.
  Fly   222 RDEAHEV----LLDQPDLADNSISLLDQFKANPYEAI-----DSSPK-------LGEGYKRLCRS 270

  Fly   294 QFPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRAT 358
            .|.|: .|||:|.||.|||.||||||||||.:.|:|::|:|||:|..|:|::|..:|.|.||...
  Fly   271 SFSPN-PSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTE 334

  Fly   359 VYQASSGRNEVVKT-RTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQ 422
            ::  ...:||...: ||      |.| .||...|..|:.|:||..:.....:.::.||.|..|..
  Fly   335 MF--DDNKNEARSSYRT------PLG-GPLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTN 390

  Fly   423 HYDFFNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLK-DNGQI 486
            :||||.|.||..... |||:||.:|||.|...|||||||.:...|..:||.|:.||||. |...:
  Fly   391 YYDFFKKRNSESKGF-GDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYNLNGDTHDM 454

  Fly   487 DTQTLHAACPVIVGSKWVCNKWIRE 511
            :..|:||||||..|||||...||.|
  Fly   455 EPTTMHAACPVFHGSKWVMTAWIHE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	44/121 (36%)
		TPR_11	179..250	CDD:290150	17/72 (24%)
		TPR repeat	179..213	CDD:276809	8/35 (23%)
		TPR repeat	218..248	CDD:276809	7/29 (24%)
		P4Hc	339..510	CDD:214780	69/172 (40%)
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	44/121 (36%)
		P4Hc	316..478	CDD:214780	69/171 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461769
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910