Protein Alignment PH4alphaPV and PH4alphaSG1

DIOPT Version :10

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 165/539 - (30%)
• Similarity: 264/539 - (48%)
• Gaps: 55/539 - (10%)

  Fly    18 VLLLLLRQAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSL-RLENDKA 81
            ::|.||........:.::::.:.:|||:||.:::..::|....:::.:.::|.:..: ..:||
  Fly     6 IILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDEQQND-- 68

  Fly    82 RSSTEEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQ---------VERIQELREHMPTHTD 137
            |...|||..||:|:|..|:|:..|   |:..:.|||..|.         .:.::::....||..|
  Fly    69 RGDLEEYFGNPINAFITIKRLVHD---WKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQED 130

  Fly   138 VEEAVTALDRIQSTYGLKVPEISHGFLNGKQYN---VSLTVLDTYAMGQILFDQKNYLAAASWIY 199
            :..|..||.|:|:.|.|....::.|.|:..:.|   .||:..|.:.:|:.|.:.|.|...:.|
  Fly   131 LHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEW-- 193

  Fly   200 QSVVLMEAFSM--AAPLE-ISKNEVRMVYAETL---------LKLNQHADALKVVNIALTDNPHD 252
                |:||...  ..||. ||.|...:...|.|         |||     |.|:.|..|...|..
  Fly   194 ----LLEARKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKL-----AYKLNNEILDKKPDH 249

  Fly   253 IKLLLKKSEIETMIRTGTNNAPPVKVQATGVP--------TAYQIGCRGQF--PPSADSKLYC-L 306
            .:.|..|...|..:....:.||..:|:...:.        ..|...|||:.  .|.....|.| |
  Fly   250 EEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWL 314

  Fly   307 YNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVK 371
            |::.. |:..|:|.|:|.:.:|||:...|:||...||..:.......::|:.|.|:.:.....|
  Fly   315 YHQGV-PYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEV- 377

  Fly   372 TRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSNMTA 436
             |.|:..|.....||...::..|:.|:||.:...:|.|||:|||:||.|:.|:||......::.:
  Fly   378 -RISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFS 441

  Fly   437 MSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGS 501
            ..|:|:.|.||||.||..||||.||.:|.||.|.:||:::||||..:...|.:|.||.|||:.||
  Fly   442 WKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGS 506

  Fly   502 KWVCNKWIREREQIFSRPC 520
            ||:||:|.....|.|.|||
  Fly   507 KWICNEWFHVGAQEFRRPC 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..166	CDD:462433	37/140 (26%)
		NrfG	179..>256	CDD:443378	23/88 (26%)
		TPR repeat	179..213	CDD:276809	8/35 (23%)
		TPR repeat	218..248	CDD:276809	10/38 (26%)
		P4Hc	339..510	CDD:214780	67/170 (39%)
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	37/140 (26%)
		P4Hc	347..515	CDD:214780	67/169 (40%)