DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and phy-3

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_507251.2	Gene:	phy-3 / 188624	WormBaseID:	WBGene00004026	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	60/233 - (25%)
Similarity:	102/233 - (43%)	Gaps:	52/233 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 LYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIK-----------ELQGMATPGLKRATV 359
            :||        :.|:.||::...|.:|:|.:::||::..           |:|..:..|....|.
Worm    77 VYN--------MLPVDMEIISWAPTLVIYRNLMSPRQTASFLNFIEQRDLEIQKTSDFGTSIETT 133

  Fly   360 YQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISD-MTGFNLYGSEMLQLMNYGLGGHYDQH 423
            ::.::|            ::.|...:.:||.:..:... :.|.||..:|....::|..||||..|
Worm   134 HRRANG------------SFIPPEDSNVTVEIKMQAQKRIPGLNLTVAEHFSALSYLPGGHYAVH 186

  Fly   424 YDF------------FNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVM 476
            ||:            .|||        |:||.|::|.|...|:||.||||:|...|....|....
Worm   187 YDYLDYRSKQDYDWWMNKT--------GNRIGTLIFVLKPAEKGGGTVFPSIGSTVRANAGDAFF 243

  Fly   477 WYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQ 514
            |:|.:.:.:.:..:.|..||:..|.|.:...|||...|
Worm   244 WFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRAYNQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528
		TPR_11	179..250	CDD:290150
		TPR repeat	179..213	CDD:276809
		TPR repeat	218..248	CDD:276809
		P4Hc	339..510	CDD:214780	49/194 (25%)
phy-3	NP_507251.2	P4Hc	102..277	CDD:214780	49/194 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3137
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.720