Protein Alignment PH4alphaPV and P4ha2

DIOPT Version :9

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_006532515.1
• Gene: P4ha2 / 18452
• MGIID: 894286
• Length: 557
• Species: Mus musculus
• Alignment Length: 566
• Identity: 179/566 - (31%)
• Similarity: 285/566 - (50%)
• Gaps: 80/566 - (14%)

  Fly    17 QVLLLLLR----------QAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSI 71
            |||:|:|.          ||:    ..||:..|..|:..|..|:.:|::|.:..|.||..::...
Mouse     4 QVLVLVLLMSWFGVLSWVQAE----FFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWA 64

  Fly    72 TSLRLENDKARSSTEEYLSNPLNSFSLIRRMNRDW-IIWQLYMDDPVGISQVERIQELREHMPTH 135
            :.:.....::.:..|.||::|:|::.|::|:|.|| .:..|.:.| .....|..:...|:..||.
Mouse    65 SKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQD-ASAGFVANLSVQRQFFPTD 128

  Fly   136 TDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQ 200
            .|...|..||.|:|.||.|....||.|.|.|.:|...|:|.|.:.:|:..:::.:|.....|:.|
Mouse   129 EDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQ 193

  Fly   201 SVVLMEAFSMAAPLEISKNEVRMVYAETLLKLNQHADALKVVNIALTDNP-HD--------IKLL 256
            .:..::|...|.   ::|:.|....:..:.:|.....|:::....|:.:| |:        .:.|
Mouse   194 VLKQLDAGEEAT---VTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERL 255

  Fly   257 LKK--------------SEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQ---FPPSADSKLY 304
            |::              :..|.:....|:..|...|        |:..|||:   ..|....||:
Mouse   256 LEEERGKSLSNQTDAGLATQENLYERPTDYLPERDV--------YESLCRGEGVKLTPRRQKKLF 312

  Fly   305 CLY---NRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGR 366
            |.|   ||.  |.|::||.|.|.....|::|.|:||:|.:||:.::.:|.|.|.||||....:|.
Mouse   313 CRYHHGNRV--PQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGV 375

  Fly   367 NEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFN--- 428
            ..|...|.||.:|..:..:|:..|:|.|:..:||..:..:|:||:.|||:||.|:.|:||..
Mouse   376 LTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPF 440

  Fly   429 ----KTNSNMTAM---------------SGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSV 474
                ||..|..|.               :|:|:||.|.|::|||.|||||||::..|::|::|:.
Mouse   441 DSGLKTEGNRLATFLNYSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTA 505

  Fly   475 VMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPC 520
            |.||||..:|:.|.:|.||||||:||.|||.|||..||.|.|.|||
Mouse   506 VFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	38/129 (29%)
		TPR_11	179..250	CDD:290150	11/70 (16%)
		TPR repeat	179..213	CDD:276809	6/33 (18%)
		TPR repeat	218..248	CDD:276809	5/29 (17%)
		P4Hc	339..510	CDD:214780	79/192 (41%)
P4ha2	XP_006532515.1	P4Ha_N	28..157	CDD:369820	38/129 (29%)
		P4Hc	348..541	CDD:214780	79/192 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100878
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820