DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and LOC110438585

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_021326960.1	Gene:	LOC110438585 / 110438585	-ID:	-	Length:	441	Species:	Danio rerio

Alignment Length:	464	Identity:	140/464 - (30%)
Similarity:	232/464 - (50%)	Gaps:	80/464 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 EEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQVERIQ-ELREHM-PTHTDVEEAVTALDRI 148
            ||.|.:|:.::.|:.|:..:.|.....:...:.:||.:..| ||:..: |.:.|::.|.:.|.|:
Zfish    23 EENLRDPVAAYKLLCRLREELIYIIETIQSIIDVSQCDEFQDELKTTLIPQYEDLDGAASGLIRL 87

  Fly   149 QSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQSVV---------- 203
            |..|.|...:|:.        ..||...:.:.:|::.:.:..:..|..|...|.:
Zfish    88 QEIYKLYPEDITK--------ETSLDADEAFHVGRVAYKEYKFQHAFLWFSYSGIRWTENSSTNE 144

  Fly   204 --LMEAFSMAA------PLEISKNEVRMVYAETLLKLNQHADALK-----VVNIALTDNPHDIKL 255
              |:...|::|      |..|       .|::.||.||.:.:.:|     :::...:.||:..:|
Zfish   145 KDLLHYLSLSAKHFGSLPWAI-------YYSQELLYLNPYDNEVKLQLNRLLHFQKSPNPNIFRL 202

  Fly   256 LLKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQFPPSADSK---LYCLYNRT-TSPFLI 316
                                     ..:.:.|:..|||:.......:   |.|.|:.: .:|.|:
Zfish   203 -------------------------DSLSSNYEALCRGEVDERTSKRQRALSCRYSTSGGNPRLM 242

  Fly   317 LAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVKTRTSKVAWFP 381
            .||:|.|.:..:|.::.:|||:|..||:.|:.:|.|.|.|:.|||  .|:.::.|.|.|: :.|.
Zfish   243 YAPVKEEELWDEPKIIRFHDVISDTEIETLKDIARPQLSRSGVYQ--DGQGKISKHRVSQ-SVFL 304

  Fly   382 DGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSNMTAMSGDRIATVL 446
            |..:|:...::.||.|:||.::..:|.|.:.|||:||.::.|.|...:.|        |||||.|
Zfish   305 DDDDPVDAHVSQRIEDVTGLSMEKAEPLLVQNYGIGGRFEPHIDALGEEN--------DRIATFL 361

  Fly   447 FYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIRE 511
            .|::|||:||||||..:..||.|::||.|.||||:.||:.|..|.||.|||:.|:|||.||||.|
Zfish   362 IYMSDVEEGGATVFIKVGIAVKPEKGSAVFWYNLQKNGESDFNTKHAGCPVLQGNKWVANKWIAE 426

  Fly   512 REQIFSRPC 520
            ..|:|.|||
Zfish   427 FGQVFRRPC 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	21/79 (27%)
		TPR_11	179..250	CDD:290150	15/93 (16%)
		TPR repeat	179..213	CDD:276809	7/51 (14%)
		TPR repeat	218..248	CDD:276809	6/34 (18%)
		P4Hc	339..510	CDD:214780	75/170 (44%)
LOC110438585	XP_021326960.1	P4Ha_N	<19..100	CDD:311993	21/76 (28%)
LOC110438585	XP_021326960.1	P4Hc	265..424	CDD:214780	74/169 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010