DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaPV and LOC110438249

DIOPT Version :9

Sequence 1:	NP_733395.1	Gene:	PH4alphaPV / 43640	FlyBaseID:	FBgn0051015	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_021324927.1	Gene:	LOC110438249 / 110438249	-ID:	-	Length:	229	Species:	Danio rerio

Alignment Length:	224	Identity:	105/224 - (46%)
Similarity:	139/224 - (62%)	Gaps:	3/224 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 PSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQ 361
            |..:.||.|.|.|.....|:|  .|.|:....|.::.|||.||..||..::.:|.|.|.||.|..
Zfish     3 PQRERKLVCRYRRGRGNPLML--FKEEVEWDQPMILRYHDFLSEGEIDTIKTLARPKLSRAQVID 65

  Fly   362 ASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDF 426
            |.||:.....:|.|:.||..:..:|:..::|.||:|:||..|..:|.||:.|||:||.|:.|||
Zfish    66 AVSGKRVSAASRVSQSAWLYEDEDPVVTQVNQRIADVTGLELQTAESLQIANYGIGGQYEPHYD- 129

  Fly   427 FNKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTL 491
            ...||.:...:.|.||||||.|::||:.|||||||::..|:.|:|||.|:|:||..||..|.:||
Zfish   130 SKLTNDSDFQLRGGRIATVLIYMSDVDIGGATVFPDVGAALQPKRGSAVLWFNLLRNGNEDIRTL 194

  Fly   492 HAACPVIVGSKWVCNKWIREREQIFSRPC 520
            ||||||.||||||.|||||...|.|.|.|
Zfish   195 HAACPVFVGSKWVANKWIRTYGQEFRRKC 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528
		TPR_11	179..250	CDD:290150
		TPR repeat	179..213	CDD:276809
		TPR repeat	218..248	CDD:276809
		P4Hc	339..510	CDD:214780	84/170 (49%)
LOC110438249	XP_021324927.1	PLN00052	28..218	CDD:177683	91/190 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010