Protein Alignment PH4alphaPV and p4ha1b

DIOPT Version :9

• Sequence 1: NP_733395.1
• Gene: PH4alphaPV / 43640
• FlyBaseID: FBgn0051015
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_999856.1
• Gene: p4ha1b / 100003675
• ZFINID: ZDB-GENE-030131-4089
• Length: 536
• Species: Danio rerio
• Alignment Length: 550
• Identity: 183/550 - (33%)
• Similarity: 276/550 - (50%)
• Gaps: 61/550 - (11%)

  Fly    12 VLLTYQVLLLLLRQAKGEESHCTSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRL 76
            ::|.:.:|..|...........||...|..||..|..|:.:|::|..:.|.:|:.|:.....|..
Zfish     1 MMLAWFLLSFLFHFLYAHNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDS 65

  Fly    77 ENDKARSSTEEYLSNPLNSFSLIRRMNRDWI-IWQLYMDDPVGISQVERIQELREHMPTHTDVEE 140
            ....|....|.:|.:|:|:|.|::|:|.:|. :..|.:.|... ..:..:...|::.||..|...
Zfish    66 LTITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTN-GFISNLTVQRQYFPTDEDQTG 129

  Fly   141 AVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQS---- 201
            |..||.|:|.||.|....||.|.|.|..:...:||.|.|.:|:|.:...:|.....|:.|:
Zfish   130 AAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQL 194

  Fly   202 ----------VVLMEAFSMA--------APLEISKNEVR-----------MVYAETLLKLNQHAD 237
                      |.:|:..|.|        ..||::|..::           :.|.|..|:..:.|:
Zfish   195 DEGEESPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAE 259

  Fly   238 ALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQ---FPPSA 299
            ..|        ...|.|.:|.|.:.:   |..:.:..|.:.:       |:..|||:   ..|..
Zfish   260 NEK--------KEEDQKRVLDKRDAQ---RKRSKDPLPERKK-------YERLCRGEGIKLTPRR 306

  Fly   300 DSKLYCLY-NRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQAS 363
            .|:|:|.| |...:|.|:|||:|.|.....|.:|.||:::|..||:.::.||.|.|:|||:....
Zfish   307 QSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPI 371

  Fly   364 SGRNEVVKTRTSKVAWFPDGYNPLTV-RLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFF 427
            :|..|....|.||.||. .||...|: |:|.||.|:||..:..:|.||:.|||:||.|:.|:||.
Zfish   372 TGVLETAPYRISKSAWL-SGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFG 435

  Fly   428 NKTNSN--MTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQT 490
            .|...:  ....:|:||||.|||::||..||||||.::..||:|::|:.|.||||..:|:.|..|
Zfish   436 RKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYST 500

  Fly   491 LHAACPVIVGSKWVCNKWIREREQIFSRPC 520
            .||||||:||:|||.||||.||.|.|.|||
Zfish   501 RHAACPVLVGNKWVSNKWIHERGQEFRRPC 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaPV	NP_733395.1	P4Ha_N	35..164	CDD:285528	39/129 (30%)
		TPR_11	179..250	CDD:290150	18/103 (17%)
		TPR repeat	179..213	CDD:276809	10/55 (18%)
		TPR repeat	218..248	CDD:276809	6/40 (15%)
		P4Hc	339..510	CDD:214780	82/173 (47%)
p4ha1b	NP_999856.1	P4Ha_N	24..153	CDD:285528	39/129 (30%)
		TPR repeat	164..199	CDD:276809	8/34 (24%)
		TPR_16	168..238	CDD:290168	13/69 (19%)
		TPR repeat	204..234	CDD:276809	7/29 (24%)
		P4Hc	347..520	CDD:214780	82/173 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100878
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820