DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31021 and zgc:152670

DIOPT Version :9

Sequence 1:	NP_733392.2	Gene:	CG31021 / 43638	FlyBaseID:	FBgn0051021	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001070123.2	Gene:	zgc:152670 / 557059	ZFINID:	ZDB-GENE-060929-954	Length:	490	Species:	Danio rerio

Alignment Length:	502	Identity:	115/502 - (22%)
Similarity:	205/502 - (40%)	Gaps:	115/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65
            :.|.|.|||.....|.:..||.:..:.:.:....:......:.||:.:.:|:.:|:|::.:..:|
Zfish    33 LFNEEENLLDTFSLYIDAEEENLKKMKSLLLLLQLGSFSNPQSPEETMRDPVAAFKLLKRLRHEW 97

  Fly    66 VGWQVYMEDLVAPEAVQKVESLLPQ--LPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSSSL 128
            |....:.:.    ...|:.::||..  :|:.|....||..:..|.:.|...|.::      :...
Zfish    98 VNIAKFTQQ----SLYQEFQTLLDYSLIPELEDINSAALGLIGLQEIYKLYPHNI------TKET 152

  Fly   129 HLSPLDCYHLGLELYEEQDYLGAAKWLQVAAH---NYTLSRHRDLFNPLGAPRWQ-------VYR 183
            .||..:.|::||..|||..:..|..|...:.:   :::.:...||...|.:..:|       :|
Zfish   153 PLSADEAYYIGLVAYEEDKFQHAFLWFLHSLNRLTDFSSTTKNDLLRFLSSSAYQFGSLPVAIY- 216

  Fly   184 DLGRTLLKLNRQCAYDAYESALRLNSQNVHLMKEAGQMELFSLRDPMEP---ILDLQPKPTVLEK 245
             .|:.|               |.|:..|..:..:.|...|..|:....|   .|:.|...: .|.
Zfish   217 -FGQKL---------------LNLDPSNEEIKVQLGLYRLIRLQRTSNPDIFTLNTQSNNS-YEA 264

  Fly   246 YCRGEV----PRHQGRLTCELN-DWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAY 305
            .|||||    .:.|..|:|..: ...:..|.|||:|.|:|..:|.||.|...|.:.||..:::..
Zfish   265 LCRGEVDERTSKRQRALSCRYSTGGGNPRLMYAPVKEEELWDEPKIIRYHDVISDTEIETLKDIA 329

  Fly   306 ERCPPNDRFELKLGISGCSISD---GYSPVLK------RINERILDMAGVEKTWDTFYIVEYAQL 361
            .  |...|.:...|:    |||   ..|..|:      ||::||.|:.|:.        ||.|:
Zfish   330 R--PELTRSQTGWGV----ISDIRTSQSVFLEEVGTVARISQRIADITGLS--------VESAE- 379

  Fly   362 APFEPFKLFRNSTKFPKLNLMNF-------------EDVE---AKVIIFLKDVTLGGAFTMPNGD 410
                            ||::.|:             ::|.   |..:|::.||.:|||....|..
Zfish   380 ----------------KLHVQNYGIGGRYTPHFDTGDEVNERTATFLIYMSDVEVGGATVFTNVG 428

  Fly   411 ILVQPKRGNVLITF---ENEE------HSTTICPIIEGTGLVMIKFI 448
            :.|:|::|:.:..:   :|.|      |:.  ||::.|...|..|:|
Zfish   429 VAVKPEKGSAVFWYNLHKNGELDLKTKHAG--CPVLVGNKWVANKWI 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	25/119 (21%)
zgc:152670	NP_001070123.2	P4Ha_N	26..150	CDD:285528	25/126 (20%)
zgc:152670	NP_001070123.2	P4Hc	318..474	CDD:214780	43/189 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583416
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930