Protein Alignment CG31021 and P4HTM

DIOPT Version :10

• Sequence 1: NP_733392.2
• Gene: CG31021 / 43638
• FlyBaseID: FBgn0051021
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_808807.2
• Gene: P4HTM / 54681
• HGNCID: 28858
• Length: 563
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 62/300 - (20%)
• Similarity: 97/300 - (32%)
• Gaps: 92/300 - (30%)

  Fly     1 MLNLERNLLQNMRDYAEKLE----EKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHM 61
            |..|:|:.:....:|.|.:.    .::||..         :.|.|.|....|...|...||..
Human   165 MKGLQRSQILPTEEYEEAMSTMQVSQLDLFR---------LLDQNRDGHLQLREVLAQTRLGN-- 218

  Fly    62 HQDWVGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSS 126
                 ||      .:.||::|::.:.:...|..:       .|.||.:|...:..|. .|..||.
Human   219 -----GW------WMTPESIQEMYAAIKADPDGD-------GVLSLQEFSNMDLRDF-HKYMRSH 264

  Fly   127 SLHLSPL--DCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHR------------DLFNPLGAP 177
            ....|.|  :.:|..|       |.|     :.|.|.....|.|            :|..||...
Human   265 KAESSELVRNSHHTWL-------YQG-----EGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVV 317

  Fly   178 R------WQVYRDLG----RTLLKLNRQCAYDA--YESALRLNSQNVHLMKEAGQMELFSLRDPM 230
            |      :..:.|.|    .|:....:..|.::  :|::.|..|.|         ..|.|:..|.
Human   318 RYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRQVSPN---------WGLPSILRPG 373

  Fly   231 EPILDLQPKPTVLEKYCRGEVPRHQG---RLTCELNDWVH 267
            .|:...||        |...||...|   .....::.|.|
Human   374 TPMTQAQP--------CTVGVPLGMGPGDHWVIPVSPWEH 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:462433	25/121 (21%)
P4HTM	NP_808807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..111
		EF-hand_7	192..252	CDD:463900	19/88 (22%)
		P4Hc	246..519	CDD:214780	39/189 (21%)