Protein Alignment CG31021 and P4HA1

DIOPT Version :9

• Sequence 1: NP_733392.2
• Gene: CG31021 / 43638
• FlyBaseID: FBgn0051021
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_000908.2
• Gene: P4HA1 / 5033
• HGNCID: 8546
• Length: 534
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 121/497 - (24%)
• Similarity: 211/497 - (42%)
• Gaps: 59/497 - (11%)

  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65
            :::.|::|:.:::||.:..|:|::.|..:.|..:.....|.:|||.::.:|:|:|:|::.::.:|
Human    31 LIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEW 95

  Fly    66 VGWQVYMEDLVAPEAVQK-VESLLPQ---LPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSS 126
                ..:|:||..:.... :.:|..|   .|..|....||:::..|...|..: .|.::|.....
Human    96 ----SELENLVLKDMSDGFISNLTIQRQYFPNDEDQVGAAKALLRLQDTYNLD-TDTISKGNLPG 155

  Fly   127 SLHLSPL---DCYHLGLELYEEQDYLGAAKWLQVAAHNY------TLSRHRDLFNPLGAPRWQVY 182
            ..|.|.|   ||:.||...|.|.||.....|::.|....      |:    |..:.|....:.||
Human   156 VKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTI----DKVSVLDYLSYAVY 216

  Fly   183 R--DLGRTLLKLNRQCAYD----------AYESALRLNSQNVHLMKEAGQMELFSLRDPMEPILD 235
            :  ||.:.||...:....|          .|...:....::|:......|.:..:........:|
Human   217 QQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVD 281

  Fly   236 LQPKPTVLEKYCRGE----VPRHQGRLTCELNDWVHS--FLAYAPIKFEDLQQDPFIILYPGSIY 294
            ..|:....|..||||    .||.|.:|.|..:|...:  |: .||.|.||....|.||.:...|.
Human   282 YLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFI-LAPAKQEDEWDKPRIIRFHDIIS 345

  Fly   295 EQEIRHVEN----AYERCPPNDRFELKLGISGCSIS-----DGY-SPVLKRINERILDMAGVE-K 348
            :.||..|::    ...|...:|....||..:...:|     .|| :||:.|||.||.|:.|:: .
Human   346 DAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVS 410

  Fly   349 TWDTFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILV 413
            |.:...:..|.....:||...|....:......:...:..|..:.::.||:.|||...|.....|
Human   411 TAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASV 475

  Fly   414 QPKRGNVLITFE-----NEEHST--TICPIIEGTGLVMIKFI 448
            .||:|..:..:.     ..::||  ..||::.|...|..|::
Human   476 WPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	29/121 (24%)
P4HA1	NP_000908.2	P4Ha_N	25..112	CDD:400573	20/84 (24%)
		TPR	205..238		8/32 (25%)
		P4Hc	345..518	CDD:214780	42/173 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149299
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940