DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31021 and CG31016

DIOPT Version :9

Sequence 1:	NP_733392.2	Gene:	CG31021 / 43638	FlyBaseID:	FBgn0051021	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	135/511 - (26%)
Similarity:	218/511 - (42%)	Gaps:	93/511 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65
            :|..:|.|:..:..||.:|.|||.::...|:::...:|.|....|:|||||::|..|:|.||:||
  Fly    38 LLEKDRELIIVLDSYATELNEKIIMLKRIVKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDW 102

  Fly    66 VGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAK--DERSSSL 128
            ...:..::..|..|.:..||.:...||.:....:|.:::..:...|..||.|:.|.  |......
  Fly   103 EKVEKLLKKPVGQEKIALVEKMREDLPVENDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGG 167

  Fly   129 HLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRWQVYRDLGRTLL--- 190
            .:|..||:.:|...:....|..|:|||. ||.:..:.:.|.....:|..:..|...|.|:|:
  Fly   168 KMSASDCFTMGTFSFMAGSYQIASKWLS-AAKDLLVDQPRKYHEVMGITKADVTLLLARSLIASG 231

  Fly   191 -------KLNRQCAYDAYESALRLNSQNVHLMKEAGQMELFSLRDPMEPILDLQPKPTV-LEKY- 246
                   .|.|...:....|||     .||.::.                   :|||:: ||.:
  Fly   232 NVSIATDMLMRDFMFGEAGSAL-----TVHFLRN-------------------KPKPSINLESWE 272

  Fly   247 --------CRGEVPRHQG-----RLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEI 298
                    ||....|..|     ||.|..|.....||..||.:.|:|..||::|.|...:.:.||
  Fly   273 SDESFNQLCRSSSRRQMGESKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEI 337

  Fly   299 RHVENAYERCPPNDR--------FELKLG---ISGCSISDG-YSP----------VLKRINERIL 341
                   |:..|..:        |.::.|   |.....:|| :.|          ||.||..||.
  Fly   338 -------EKLKPMGKPFLERAKVFRVEKGSDEIDPSRSADGAWLPHQNIDPDDLEVLNRIGRRIE 395

  Fly   342 DMAGVE-KTWDTFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMNFEDVEAKVIIFLKDVTLGGAFT 405
            ||.|:. ::......::|.....|.|...:.||..|   :|....|..|.|:.:|.:|..|||..
  Fly   396 DMTGLNTRSGSKMQFLKYGFGGHFVPHYDYFNSKTF---SLETVGDRIATVLFYLNNVDHGGATV 457

  Fly   406 MPNGDILVQPKRGNVL----ITFENEEHSTT----ICPIIEGTGLVMIKFIMKTDE 453
            .|..::.|..::|:.|    |..::.::.|.    .||:|.||.|||.::|.:.|:
  Fly   458 FPKLNLAVPTQKGSALFWHNIDRKSYDYDTRTFHGACPLISGTKLVMTRWIYELDQ 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	36/117 (31%)
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	37/121 (31%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	48/184 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452374
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990