Protein Alignment CG31021 and P4HA3

DIOPT Version :9

• Sequence 1: NP_733392.2
• Gene: CG31021 / 43638
• FlyBaseID: FBgn0051021
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_001275677.1
• Gene: P4HA3 / 283208
• HGNCID: 30135
• Length: 604
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 106/475 - (22%)
• Similarity: 172/475 - (36%)
• Gaps: 119/475 - (25%)

  Fly     5 ERNLLQNMRDYAEKLEEKI-DLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDWVGW 68
            ||.||..:|.|....|.:: ||...|.:     :...:||....::|||.:|.||:.:..|   |
Human    44 ERRLLGLLRRYLRGEEARLRDLTRFYDK-----VLSLHEDSTTPVANPLLAFTLIKRLQSD---W 100

  Fly    69 QVYMEDLVAPEAV-------QKVESLLPQLPQKEAFRKAARSVHSLTQFY--------------- 111
            :..:..|.|.|.:       :|||.   .||..|....|||::..|...|
Human   101 RNVVHSLEASENIRALKDGYEKVEQ---DLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRV 162

  Fly   112 -GYEPADLVAKDERSSSLHLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNY------------- 162
             |....||.:.....|   |:..||:.:|...|:..||..|..||:.|...:
Human   163 TGSAITDLYSPKRLFS---LTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEA 224

  Fly   163 -----------------------TLSRHRDLFNPLGAPRWQVYRDLGRTLLKLNRQCAYDAYESA 204
                                   :|||...|::|..       :.:.|.:||..|
Human   225 SLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDN-------KRMARNVLKYER---------- 272

  Fly   205 LRLNSQNVHLMKEA----GQMELFSLRDPMEPILD-LQPKPTVLEKYCRGEVPRHQGRLTCELND 264
            |...|.| |::.||    ..:.....||..|.:.. |..:||:.      ::|    .|.|....
Human   273 LLAESPN-HVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLY------QIP----SLYCSYET 326

  Fly   265 WVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYER-------CPPNDRFELKLGISG 322
            ..:::|...||:.|.:..:|:|.||...:.:.|.:.:....|.       .....:.:::..||.
Human   327 NSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSVVASGEKQLQVEYRISK 391

  Fly   323 CS-ISDGYSPVLKRINERILDMAGVE---KTWDTFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMN 383
            .: :.|...|.|..:|.||..:.|::   ...:...:|.|.....:||......|...|...:.:
Human   392 SAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKS 456

  Fly   384 FEDVEAKVIIFLKDVTLGGA 403
            ...| |..:|:|..|..|||
Human   457 GNRV-ATFMIYLSSVEAGGA 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	36/137 (26%)
P4HA3	NP_001275677.1	P4Ha_N	58..159	CDD:285528	28/111 (25%)
		TPR_12	186..252	CDD:290160	10/65 (15%)
		P4Hc	356..>478	CDD:214780	25/121 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149272
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.830