Protein Alignment CG31021 and dpy-18

DIOPT Version :9

• Sequence 1: NP_733392.2
• Gene: CG31021 / 43638
• FlyBaseID: FBgn0051021
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_499464.1
• Gene: dpy-18 / 176569
• WormBaseID: WBGene00001077
• Length: 559
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 119/526 - (22%)
• Similarity: 197/526 - (37%)
• Gaps: 121/526 - (23%)

  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65
            :|..|||:.:.:..|....||::..:....|:|:...|.:.|:..|.::||:|:|.||:....||
 Worm    28 LLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKDITNPINAFLLIKRKIFDW 92

  Fly    66 VGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLT-QFYG--YEPAD---------- 117
                            :::||       |....||...|.|:| ..||  |..||
 Worm    93 ----------------KEIES-------KMNANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLL 134

  Fly   118 -------LVAKDERSSSLH-------LSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHR 168
                   |..||.....::       .|..||:.:....|.|.|:.....|::.|..     |..
 Worm   135 RLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQR-----RLG 194

  Fly   169 DLFNPLGAPRWQVYRDLGRTLLKLNRQCAYDAYESALRLNSQ-------------NV----HLMK 216
            |...|..... .:...|...|.|.|.      .:.||:|..:             ||    .|::
 Worm   195 DEVEPTVEVE-DILEYLAFALYKQNN------LKHALKLTEELYKMNPTHPRAKGNVKWYEDLLE 252

  Fly   217 EAGQMELFSLRDPMEPILDLQP-------KPTVLEKYCRGEVPRHQ---GRLTCEL-NDWVHSFL 270
            :.| :....:|..:.||.:.:|       :.|:.|..||.|||..|   .||.|.. .|  ..||
 Worm   253 QEG-VRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISRLYCYYKRD--RPFL 314

  Fly   271 AYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYE----RCPPNDRFELKLGISGCSIS----- 326
            .|||||.|..:.:|..:|:...|.:.|:..::...:    |...:|....||..:...||
 Worm   315 VYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWL 379

  Fly   327 -DGYSPVLKRINERILDMAGVE-KTWDTFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMNFEDVE- 388
             :....|::.:|:||..|..:| :|.:...|..|.....::|.  |.::.|...   .:||.:.
 Worm   380 KEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPH--FDHAKKEES---KSFESLGT 439

  Fly   389 ----AKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITFE-------NEEHSTTICPIIEGTGL 442
                |.|:.::...:.||..........:.|.:.:.|..:.       |.:.....||::.|...
 Worm   440 GNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKW 504

  Fly   443 VMIKFI 448
            |..|:|
 Worm   505 VSNKWI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	33/137 (24%)
dpy-18	NP_499464.1	P4Ha_N	21..152	CDD:285528	36/146 (25%)
		P4Hc	338..511	CDD:214780	34/178 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010