Protein Alignment CG2246 and PDA1

DIOPT Version :10

• Sequence 1: NP_733389.2
• Gene: CG2246 / 43637
• FlyBaseID: FBgn0039790
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_011105.4
• Gene: PDA1 / 856925
• SGDID: S000000980
• Length: 420
• Species: Saccharomyces cerevisiae
• Alignment Length: 329
• Identity: 60/329 - (18%)
• Similarity: 99/329 - (30%)
• Gaps: 125/329 - (37%)

  Fly     7 KLGSVRPPKRCR--SDMDNTSTSDIVIINGNSHPDLANMVAERMGIKNG-GCSV------FHKSN 62
            ||.|:....||.  :.|...|...:          ||.::..|.|:..| |.|:      |:..|
Yeast   130 KLDSIITSYRCHGFTFMRGASVKAV----------LAELMGRRAGVSYGKGGSMHLYAPGFYGGN 184

  Fly    63 RETIVEI--------SDSVRGKDIYIIQTGTKDANN--------NIMEL--LIMAYACK------ 103
            .....::        :...:.:|..........|:|        |:.:|  |.:.:.|:
Yeast   185 GIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNKYGM 249

  Fly   104 -TSSARSIVGVIPYLPYSKQCKMRKRGCIVSKL---------------LAKMMCTSGLTHIITMD 152
             |:::||          |...:..|||..:..|               .||..|.||
Yeast   250 GTAASRS----------SAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSG-------- 296

  Fly   153 LHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLR------- 210
                              ..|.:|:|     ..||.......:||...:.....:.:|
Yeast   297 ------------------KGPLVLEY-----ETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIA 338

  Fly   211 --------LGLAVIHGEQKETDA-------DEVDGRYSPPPTSAYSNLLGNSVEMCLPATP--RN 258
                    ||:|. ..|.|..|.       ::|:...:.||..|..::|...|.:....||  |.
Yeast   339 GLKMHLIDLGIAT-EAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRG 402

  Fly   259 STPQ 262
            ..|:
Yeast   403 RIPE 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2246	NP_733389.2	Pribosyltran_N	29..144	CDD:433483	27/161 (17%)
		Pribosyl_synth	185..400	CDD:434046	21/102 (21%)
PDA1	NP_011105.4	TPP_enzymes	50..394	CDD:470272	56/315 (18%)