Protein Alignment CG2246 and PRS5

DIOPT Version :9

• Sequence 1: NP_001189321.1
• Gene: CG2246 / 43637
• FlyBaseID: FBgn0039790
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_014580.1
• Gene: PRS5 / 854093
• SGDID: S000005422
• Length: 496
• Species: Saccharomyces cerevisiae
• Alignment Length: 506
• Identity: 156/506 - (30%)
• Similarity: 232/506 - (45%)
• Gaps: 142/506 - (28%)

  Fly    25 STSDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDAN 89
            |.|:||:..|:|||:|...:.|.:.|......:...||.||.:.:.:|||.||:||||:|....|
Yeast     2 SMSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGCGQVN 66

  Fly    90 NNIMELLIMAYACKTSSARSIVGVIPYLPYSKQCKM---RKRGCIVSK----------------- 134
            :..|:|||:..|||::||..:..|:|||.||:|..:   .|...|:||
Yeast    67 DTFMQLLILISACKSASASRVTAVMPYLCYSRQPDIPYTAKGAPIISKPKENYTFESHPGTPVSS 131

  Fly   135 ----------------------------------------------------------------- 134
                                                                             
Yeast   132 SLMTQRPGAESSLKSLDSAIRSTINLENPQPIRTPNSSATANNNFDIKKTLSFSRIPMIPGGKLQ 196

  Fly   135 ----------------------------LLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRA 171
                                        |:|.::..:|..|:||||||..:..||||||||||..
Yeast   197 NTSNSTDAGELFNAQNAGYKLWVVQAGTLIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYC 261

  Fly   172 SPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGEQKETDADEVDGRYSPPP 236
            .|....|||..||||:::|||:.:.|.||:|.:.|:.|.|..|:||   ||..:..:.|    ||
Yeast   262 KPIAQNYIQHRIPDYQDAVIVSPDAGGAKRATAIADALELSFALIH---KERRSQLLKG----PP 319

  Fly   237 TSAYSNLLGNSVEMCLPATPR----------NSTPQHAPTSSA--RQRTTSVS--VGVPEHIVKV 287
            .:..::  |.|    ||.:||          |:|...|...:|  .::|||.|  .....:..|.
Yeast   320 DATLTS--GGS----LPVSPRPLVTTLVSSQNTTSSGATGVAALEMKKTTSTSSTSSQSSNSSKF 378

  Fly   288 KPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPI 352
            .....:||||..::.|:||||:|.......||::||:.|:.|:|.|.|||:.|.||..::.:|.|
Yeast   379 VQTTMLVGDVRNKVCIIVDDLVDTSYTITRAAKLLKDQGSTKVYALITHGVFSGDALERIGQSSI 443

  Fly   353 DEIVVTNTIPHE--IQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFRN 401
            |:::::||:|.:  :|.|...::..||:|.:|.||||||||.||:|.||.:
Yeast   444 DKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGESISMLFEH 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2246	NP_001189321.1	PrsA	25..400	CDD:223538	155/503 (31%)
		Pribosyltran_N	29..144	CDD:290508	46/227 (20%)
		Pribosyl_synth	185..400	CDD:291252	83/230 (36%)
PRS5	NP_014580.1	PrsA	2..493	CDD:223538	155/503 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I1190
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60704
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10210
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920