Protein Alignment CG2246 and Prps1l1

DIOPT Version :10

• Sequence 1: NP_733389.2
• Gene: CG2246 / 43637
• FlyBaseID: FBgn0039790
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001099148.1
• Gene: Prps1l1 / 298954
• RGDID: 1306328
• Length: 318
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 153/378 - (40%)
• Similarity: 219/378 - (57%)
• Gaps: 63/378 - (16%)

  Fly    28 DIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNI 92
            :|.|.:|:||.||:..:.||:|::.|.......||:||.|||.:||||:|:||:|:|..:.|:::
  Rat     3 NIKIFSGSSHQDLSQKITERLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDSL 67

  Fly    93 MELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK-RGCIVSKLLAKMMCTSGLTHIITMDLHQK 156
            ||||||..|||.:||..:..|||..||::|.|..| |..:.:||:|.|:..:|..||||||||..
  Rat    68 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPMSAKLIANMLSIAGADHIITMDLHAS 132

  Fly   157 EIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGEQK 221
            :||||||||||||.|.|.:|::|:|:|.|:||..||:.:.|.||:..|.|:.|.:..|:||.|:|
  Rat   133 QIQGFFDIPVDNLYAEPAVLKWIKENISDWRNCTIVSPDAGGAKRVTSIADHLNVDFALIHKERK 197

  Fly   222 ETDADEVDGRYSPPPTSAYSNLLGNSVEMCLPATPRNSTPQHAPTSSARQRTTSVSVGVPEHIVK 286
            :  |:|||
  Rat   198 K--ANEVD--------------------------------------------------------- 203

  Fly   287 VKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESP 351
               .:.:||||..|:||:|||:.|.......||:.|...||.::|.:.|||:.|..|..:::.:.
  Rat   204 ---RMVLVGDVKERVAILVDDMADTCGTICYAADKLLSEGATRVYAILTHGIFSGPAIARINGAC 265

  Fly   352 IDEIVVTNTIPHEIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFRNVTL 404
            .:.:|||||||.|.:..||.||:.||||:::||||||.||.||:||||.:|.|
  Rat   266 FEAVVVTNTIPQEDKMKQCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2246	NP_733389.2	Pribosyltran_N	29..144	CDD:433483	52/115 (45%)
		Pribosyl_synth	185..400	CDD:434046	71/214 (33%)
Prps1l1	NP_001099148.1	PrsA	1..314	CDD:440230	150/372 (40%)