Protein Alignment CG2246 and Prps1

DIOPT Version :9

• Sequence 1: NP_001189321.1
• Gene: CG2246 / 43637
• FlyBaseID: FBgn0039790
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_067438.1
• Gene: Prps1 / 19139
• MGIID: 97775
• Length: 318
• Species: Mus musculus
• Alignment Length: 378
• Identity: 154/378 - (40%)
• Similarity: 220/378 - (58%)
• Gaps: 63/378 - (16%)

  Fly    28 DIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNI 92
            :|.|.:|:||.||:..:|:|:|::.|.......||:||.|||.:||||:|:||:|:|..:.|:|:
Mouse     3 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNL 67

  Fly    93 MELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK-RGCIVSKLLAKMMCTSGLTHIITMDLHQK 156
            ||||||..|||.:||..:..|||..||::|.|..| |..|.:||:|.|:..:|..||||||||..
Mouse    68 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHAS 132

  Fly   157 EIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGEQK 221
            :||||||||||||.|.|.:|::|:|:|.::||..||:.:.|.||:..|.|:||.:..|:||.|:|
Mouse   133 QIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERK 197

  Fly   222 ETDADEVDGRYSPPPTSAYSNLLGNSVEMCLPATPRNSTPQHAPTSSARQRTTSVSVGVPEHIVK 286
            :  |:|||
Mouse   198 K--ANEVD--------------------------------------------------------- 203

  Fly   287 VKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESP 351
               .:.:||||..|:||:|||:.|.......||:.|...||.::|.:.|||:.|..|..:::.:.
Mouse   204 ---RMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNAC 265

  Fly   352 IDEIVVTNTIPHEIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFRNVTL 404
            .:.:|||||||.|.:...|.||:.||||:::||||||.||.||:||||.:|.|
Mouse   266 FEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2246	NP_001189321.1	PrsA	25..400	CDD:223538	151/372 (41%)
		Pribosyltran_N	29..144	CDD:290508	54/115 (47%)
		Pribosyl_synth	185..400	CDD:291252	70/214 (33%)
Prps1	NP_067438.1	PrsA	1..313	CDD:223538	150/371 (40%)
		Binding of phosphoribosylpyrophosphate. /evidence=ECO:0000255	212..227		7/14 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60704
OrthoDB	1	1.010	-	-		D1043963at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830