Protein Alignment CG2246 and prps1a

DIOPT Version :10

• Sequence 1: NP_733389.2
• Gene: CG2246 / 43637
• FlyBaseID: FBgn0039790
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001346823.1
• Gene: prps1a / 140620
• ZFINID: ZDB-GENE-011212-5
• Length: 320
• Species: Danio rerio
• Alignment Length: 380
• Identity: 155/380 - (40%)
• Similarity: 221/380 - (58%)
• Gaps: 65/380 - (17%)

  Fly    28 DIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNI 92
            :|.|.:|:|||||:..:|:|:|::.|.......||:||.|||.:||||:|:||:|:|..:.|:|:
Zfish     3 NIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNL 67

  Fly    93 MELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK---RGCIVSKLLAKMMCTSGLTHIITMDLH 154
            ||||||..|||.:||..:..|||..||::|.|..|   |..|.:||:|.|:..:|..||||||||
Zfish    68 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKVGSRAPISAKLVANMLSVAGADHIITMDLH 132

  Fly   155 QKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGE 219
            ..:||||||||||||.|.|.:|::|:|:|.:::|..||:.:.|.||:..|.|:||.:..|:||.|
Zfish   133 ASQIQGFFDIPVDNLYAEPAVLKWIKENINEWKNCTIVSPDAGGAKRVTSIADRLNVDFALIHKE 197

  Fly   220 QKETDADEVDGRYSPPPTSAYSNLLGNSVEMCLPATPRNSTPQHAPTSSARQRTTSVSVGVPEHI 284
            :|:  |:|||
Zfish   198 RKK--ANEVD------------------------------------------------------- 205

  Fly   285 VKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDE 349
                 .:.:||||..|:||:|||:.|.......||:.|...||.|:|.:.|||:.|..|..:::.
Zfish   206 -----RMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAISRINN 265

  Fly   350 SPIDEIVVTNTIPHEIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFRNVTL 404
            :..:.:|||||||.|.:...|.||:.||||:::||||||.||.||:||||.:|.|
Zfish   266 ANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2246	NP_733389.2	Pribosyltran_N	29..144	CDD:433483	55/117 (47%)
		Pribosyl_synth	185..400	CDD:434046	70/214 (33%)
prps1a	NP_001346823.1	PrsA	1..316	CDD:440230	152/374 (41%)