DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9717 and SUL2

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_013193.1	Gene:	SUL2 / 850781	SGDID:	S000004082	Length:	893	Species:	Saccharomyces cerevisiae

Alignment Length:	580	Identity:	154/580 - (26%)
Similarity:	255/580 - (43%)	Gaps:	108/580 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GSEVSLDIPTN-TLYHTS----RDCIVQEEQGPDESCLE--GTQSCCSNLWSNIFRKKTLYKRFP 74
            ||::....|:: :||..|    .:..|..::..|.|...  ..:..||.|.|          .||
Yeast    70 GSKIDYFNPSDVSLYDNSVSQFEETTVSLKEYYDHSIRSHLTVKGACSYLKS----------VFP 124

  Fly    75 ILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFIYIFIGSSKDV 139
            |:.|||.|...:...|::|||::...::||:::||.:|.|..|||||:.|:|.:.|.|..:||||
Yeast   125 IINWLPHYNFSWFTADLIAGITIGCVLVPQSMSYAQVATLPAQYGLYSSFIGAYSYSFFATSKDV 189

  Fly   140 PIGPTAISALLSFQIA---------GGSW----QIATLLTFLTGLIEILMGVFRLGFLIDFVSGP 191
            .|||.|:.:|.:.::.         |.|.    .|||.|..|.|:|...:|..|||||::.:|..
Yeast   190 CIGPVAVMSLQTAKVIADVTAKYPDGDSAITGPVIATTLALLCGIISAAVGFLRLGFLVELISLN 254

  Fly   192 VGAGFTSAVSLIIFSSQMKDFLGIKTSGNTFLQVWISIVNDIHNISWP----DFILGIVCITLLL 252
            ..|||.:..:..|...|:...:|..:..||....:..::..:.::  |    |.:.|::.:.||.
Yeast   255 AVAGFMTGSAFNILWGQVPALMGYNSLVNTRAATYKVVIETLKHL--PDTKLDAVFGLIPLFLLY 317

  Fly   253 SLRALASCTLGPK------EGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNGK---EN 308
            ..:.... |.||:      .......|::...::....:||.:::.....:| |....||   |.
Yeast   318 VWKWWCG-TYGPRLNDRYNSKNPRLHKIIKWTYFYAQASRNGIIIIVFTCIG-WAITRGKSKSER 380

  Fly   309 LVKTVGFVPKGLPS---FQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLET 370
            .:..:|.||.||..   |..||                      .::|.||..|....::.|||.
Yeast   381 PISILGSVPSGLKEVGVFHVPP----------------------GLMSKLGPNLPASIIVLLLEH 423

  Fly   371 MAVVQAFADGKPTD----ATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYT 431
            :|:.::|  |:..|    ..|||||.||.|:..:|.....:.|..:|.|:.....|||.||.|::
Yeast   424 IAISKSF--GRINDYKVVPDQELIAIGVSNLLGTFFNAYPATGSFSRSALKAKCNVRTPLSGLFS 486

  Fly   432 SVIVIIALLYLTPCFYYIPKAALASIIIAAVI-FMVQYRVIKPMWHSKKTDLIPGLGAFFACLVL 495
            ...|::||..||..|:|||||.|:::||.||. .:..|:.....|.....|        |.|.::
Yeast   487 GSCVLLALYCLTGAFFYIPKATLSAVIIHAVSDLLASYQTTWNFWKMNPLD--------FICFIV 543

  Fly   496 PLQLGILVGIGINVVFIL-YQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVRKV 554
            .:.:.:...|...:.|.: :..|...|::                    .||:.:|:.:|
Yeast   544 TVLITVFASIEDGIYFAMCWSCAMLILKV--------------------AFPAGKFLGRV 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	140/516 (27%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	4/21 (19%)
SUL2	NP_013193.1	SUL1	118..827	CDD:223732	143/532 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341589
Domainoid	1	1.000	211	1.000	Domainoid score	I497
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I705
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm9191
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
TreeFam	1	0.960	-	-
	12	11.750