DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9717 and Slc26a5

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_110467.1	Gene:	Slc26a5 / 83819	RGDID:	69334	Length:	744	Species:	Rattus norvegicus

Alignment Length:	513	Identity:	139/513 - (27%)
Similarity:	235/513 - (45%)	Gaps:	115/513 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KKTLYKRFPILVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFI 129
            :..:|...||..|||.|| |:|:.||:|:|||..:..:||.||:|.:|.:...:|||:.|....:
  Rat    58 RNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIM 122

  Fly   130 YIFIGSSKDVPIGPTAISALL-----------SFQIAGG-------------SWQIATLLTFLTG 170
            |.|.|:|:.:.|||.|:.:|:           ...|.||             ..::|..:|.|:|
  Rat   123 YCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSG 187

  Fly   171 LIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKT---SGNTFLQVWISIVND 232
            :|:..:||.|.||:..:::.|:..|||:|.::.:|:|.:|...|:||   ||
  Rat   188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSG------------- 239

  Fly   233 IHNISWPDFILGIV--CITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTA 295
                     |..:|  .:.:|.:::.|..|:||                  :|     |:|.|
  Rat   240 ---------IFSVVYSTVAVLQNVKNLNVCSLG------------------VG-----LMVFG-- 270

  Fly   296 GLGYWLFVNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVNET---TGEVLQEAQSFWDMVSTLGS 357
                 |.:.|||...:   |..| ||:  |.|....|||..|   .|..|.|:.|. |:|.||..
  Rat   271 -----LLLGGKEFNER---FKEK-LPA--PIPLEFFAVVMGTGISAGFNLHESYSV-DVVGTLPL 323

  Fly   358 GL------------------IVVPLIALLETMAVVQAFAD--GKPTDATQELIASGVCNVANSFV 402
            ||                  |.:.::....|:::.:..|:  |...|..|||||.|:||...|..
  Rat   324 GLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLF 388

  Fly   403 QGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAV--IFM 465
            |....:..::|..:...:|.:|||:....|:::::.:|.....|..:|:|.|::|:|..:  :||
  Rat   389 QTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFM 453

  Fly   466 VQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPKLRI 523
             |:..:...|.:.|.:|...|..|.:.|.|.|..|::..:.|.::.::|:...|...:
  Rat   454 -QFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	138/505 (27%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913
Slc26a5	NP_110467.1	sulP	66..709	CDD:273284	138/505 (27%)
		STAS_SulP_like_sulfate_transporter	526..694	CDD:132913
		STAS	589..>683	CDD:279997
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	720..744
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710