DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9717 and Slc26a5

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_109652.3	Gene:	Slc26a5 / 80979	MGIID:	1933154	Length:	744	Species:	Mus musculus

Alignment Length:	568	Identity:	150/568 - (26%)
Similarity:	252/568 - (44%)	Gaps:	132/568 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DIPTNT-LYHTSRDC----IVQEEQGPDESCLEG-------TQSCCSNLWSNIFRKKTLYKRFPI 75
            :||..| .|:..|..    ::||.....:...|.       ..:|......||     :|...||
Mouse     8 EIPAETQRYYVERPIFSHPVLQERLHVKDKVTESIGDKLKQAFTCTPKKIRNI-----IYMFLPI 67

  Fly    76 LVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFIYIFIGSSKDV 139
            ..|||.|| |:|:.||:|:|||..:..:||.||:|.:|.:...:|||:.|....:|.|.|:|:.:
Mouse    68 TKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHI 132

  Fly   140 PIGPTAISALL-----------SFQIAGG-------------SWQIATLLTFLTGLIEILMGVFR 180
            .|||.|:.:|:           ...|.||             ..::|..:|.|:|:|:..:||.|
Mouse   133 SIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCR 197

  Fly   181 LGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKT---SGNTFLQVWISIVNDIHNISWPDFI 242
            .||:..:::.|:..|||:|.::.:|:|.:|...|:||   ||                      |
Mouse   198 FGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSG----------------------I 240

  Fly   243 LGIV--CITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNG 305
            ..:|  .:.:|.:::.|..|:||                  :|     |:|.|       |.:.|
Mouse   241 FSVVYSTVAVLQNVKNLNVCSLG------------------VG-----LMVFG-------LLLGG 275

  Fly   306 KENLVKTVGFVPKGLPSFQPPPFHMDAVVNET---TGEVLQEAQSFWDMVSTLGSGL-------- 359
            ||...:   |..| ||:  |.|....|||..|   .|..|.|:.|. |:|.||..||
Mouse   276 KEFNER---FKEK-LPA--PIPLEFFAVVMGTGISAGFNLHESYSV-DVVGTLPLGLLPPANPDT 333

  Fly   360 ----------IVVPLIALLETMAVVQAFAD--GKPTDATQELIASGVCNVANSFVQGLRSNGGIA 412
                      |.:.::....|:::.:..|:  |...|..|||||.|:||...|..|....:..::
Mouse   334 SLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLS 398

  Fly   413 RGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAV--IFMVQYRVIKPMW 475
            |..:...:|.:|||:....|:::::.:|.....|..:|:|.|::|:|..:  :|| |:..:...|
Mouse   399 RSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFM-QFSDLPFFW 462

  Fly   476 HSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPKLRI 523
            .:.|.:|...|..|.:.|.|.|..|::..:.|.::.::|:...|..::
Mouse   463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	138/505 (27%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913
Slc26a5	NP_109652.3	sulP	66..709	CDD:273284	138/505 (27%)
		STAS_SulP_like_sulfate_transporter	526..694	CDD:132913
		STAS_anti-anti-sigma_factors	589..683	CDD:132914
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	720..744
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710