DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9717 and CG5404

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster

Alignment Length:	556	Identity:	181/556 - (32%)
Similarity:	305/556 - (54%)	Gaps:	64/556 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYA 122
            |.|     |:.|::..|:..|||.|..::...|.:|||::.||:||:::|.|.:|||..:|||.:
  Fly    39 NKW-----KRRLHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCS 98

  Fly   123 CFLGCFIYIFIGSSKDVPIGPTAISALLSFQI-AGGSWQIATLLTFLTGLIEILMGVFRLGFLID 186
            .|:|..||:..||...|.||||::.||:|.|. .|...:.|.|||||:|:::|:||..|:||:.:
  Fly    99 AFIGPLIYMVFGSIDKVIIGPTSLVALVSVQFTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFE 163

  Fly   187 FVSGPVGAGFTSAVSLIIFSSQMKDFLGIKTSGNTFLQVWISIVNDIHNIS-------WPDFILG 244
            |:|.||...|:||.::::..||:|..||||       .:...::|.:..:|       ..|.|:|
  Fly   164 FISMPVIKAFSSATAILVIESQLKVLLGIK-------YLVAGLMNSVGMLSSRIEESNMADLIMG 221

  Fly   245 IVCITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWT-IGTARNALLVCGTAGLGY-WLFVNGK- 306
            :..|..||.|..|.......|..|      :..||.. :.|:||.|:|...|.:.: |:...|:
  Fly   222 VCAIVFLLLLELLDRVANNEKRNK------ILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQV 280

  Fly   307 -----ENLVKTVGFVPKGLPSFQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIA 366
                 :|.:.|       ||:|..|.||:         |..:...|.|:::..|..|:||:|::.
  Fly   281 PYALSKNALST-------LPNFTVPSFHI---------ETAERNYSIWEVLKELNIGIIVIPIVG 329

  Fly   367 LLETMAVVQAFADGKPT-----DATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQL 426
            :|..:::      ||.|     |..|||:..|:||:..|.||.:.|:|...|.||..|.|:||.:
  Fly   330 ILTNISI------GKLTPKGLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPM 388

  Fly   427 SNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFFA 491
            :|||..:||::||.||:|.|.|||:|.||:|:|.::..::.:::...:|...|.|....|..|..
  Fly   389 ANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLLDFKLPMRLWRDSKRDFATWLLCFCV 453

  Fly   492 CLVLPLQLGILVGIGINVVFILYQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVRKVIN 556
            .::..:::|:.|.|.:..:.:|:..|||::|:: :.....::|:.:||...:.||::.::|:.:.
  Fly   454 SVLFGVEVGLFVSIVVTALHLLFLWARPEIRVK-IEQLDEMQYIRVTPSNGIYFPAINYLRERVL 517

  Fly   557 KQGQKS--TLPVVIDCTHIYGADFTAAKVISTMVMD 590
            |..:::  .:.||||...|.|.|:|||:.||.:..|
  Fly   518 KACEQADFRITVVIDGQRISGMDYTAAQGISKLSSD 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	177/540 (33%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	20/59 (34%)
CG5404	NP_650482.1	sulP	50..557	CDD:273284	177/540 (33%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	19/56 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439013
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	10	9.900