DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9717 and Slc26a10

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_001128067.2	Gene:	Slc26a10 / 366909	RGDID:	1564851	Length:	684	Species:	Rattus norvegicus

Alignment Length:	706	Identity:	168/706 - (23%)
Similarity:	289/706 - (40%)	Gaps:	156/706 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSQRADSGHTNSGFN---GGSEVSLDIPTNTLYHTSRDCIVQEEQGPDESCL-------EGTQSC 55
            :|.|.....|::.|.   ||:|                   ||.:.|.|.||       ....|.
  Rat    31 LSSRFREPLTHARFQELFGGAE-------------------QEPELPAEPCLPWLCRLRRRRASA 76

  Fly    56 CS--NLWSNIFRKKTLYKRFPILVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQ 117
            ||  ..|      :.|..|.|.|.|||||: :.::.||.||||:|.:..:||.:|:|.:..:...
  Rat    77 CSGPGAW------RVLLARLPPLRWLPQYRWRAWLLGDAVAGITVGVVHVPQGMAFALLTSVPPV 135

  Fly   118 YGLYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQI---------AGGSWQI------------ 161
            :|||..|....||..:|:.:.:..|..|:.:|::..:         ||....|
  Rat   136 FGLYTSFFPVLIYSLLGTGRHLSTGTFAVLSLMTGSVVERVVPEPLAGNLSGIEREKLEAQRIGA 200

  Fly   162 ATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKTSGN----TF 222
            |..:.|.:|.:.:.|.|.:||.|..|:|.||....||..:|.:..||:...||:.....    :.
  Rat   201 AAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLVSQLPSLLGLSLPRQIGCFSL 265

  Fly   223 LQVWISIVNDIHNISWPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARN 287
            .:...::::.::..|..:..:..:.:.||:.::.|         ......:|.|.|...:.....
  Rat   266 FKTLAAVLSALNQSSPAELTISALSLALLVPVKEL---------NVRFRDRLPTPIPGEVVMVLL 321

  Fly   288 ALLVCGTAGLGYWLFVNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVNETTGEVLQEAQSFWDMV 352
            |.::|.|:.|      :.:.| |:.||.:|.|.|  ||....:|                  |:.
  Rat   322 ATVLCFTSSL------DSRYN-VQVVGLLPGGFP--QPLLPTLD------------------DLP 359

  Fly   353 STLGSGLIVVPLIALLETMAVVQAFAD--GKPTDATQELIASGVCNVANSFVQGLRSNGGIARGA 415
            ..|...| .:.|:....:.::...:||  ....|..|||:|.||.|:.:|......::..:|..:
  Rat   360 RILADSL-PISLVTFAVSTSLASIYADKYSYTIDPNQELLAHGVSNLISSLFSCFPNSATLATTS 423

  Fly   416 ILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFM-VQYRVIKPMWHSKK 479
            :|..:|..||||.|::..:|:..||:|.|.|||:|||.||.|.|:::..| .|.:.:..:||..:
  Rat   424 LLVDAGGNTQLSGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQMFFQMQELPQLWHVSR 488

  Fly   480 TDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPKLRIETLATTTGL-------KYLML 537
            .|....:..:.|.:.|.:.||:.||:.:::|.::.:..|.|.....||..|.|       ..|:.
  Rat   489 VDFAVWMVTWVAVVTLNVDLGLAVGVVVSMVTVVCRTQRVKCLALGLAEGTELYRPIRESHKLLQ 553

  Fly   538 TPDRCLI-------FPSMEFVRKVI---------NKQGQKSTLPVVIDCTHIYGADFTAAK---- 582
            .|..|::       |.:.....:|:         .|.|.:....|::|.:.:..||...|:
  Rat   554 VPGLCILSYPAPLYFATRGQFHRVLEWHLGLGERTKPGAEPIRVVILDFSGVTFADAAGAREVVQ 618

  Fly   583 --------------------VISTM----VMDFKLREQPLFFYNLQPRVAQVFEGL 614
                                |:.|:    ::|....||  .|.::|...|...|.|
  Rat   619 LTRRCQDDGICLLLAQCNDLVLKTLTRAGLLDSMTPEQ--LFVSVQDAAAHALERL 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	146/612 (24%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	20/121 (17%)
Slc26a10	NP_001128067.2	sulP	91..664	CDD:273284	146/611 (24%)
Slc26a10	NP_001128067.2	STAS_SulP_like_sulfate_transporter	553..661	CDD:132913	17/109 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810