DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9717 and Slc26a11

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_038943458.1	Gene:	Slc26a11 / 360670	RGDID:	1306178	Length:	593	Species:	Rattus norvegicus

Alignment Length:	586	Identity:	226/586 - (38%)
Similarity:	330/586 - (56%)	Gaps:	35/586 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 CCSNLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYG 119
            |||        :..|.:|.|:|.|||.|...::..|::||:||.|||||||||||.:|||..|||
  Rat     7 CCS--------RADLRRRLPVLAWLPNYSLRWLRMDVIAGLSVGLTVIPQALAYAEVAGLPPQYG 63

  Fly   120 LYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQIAGGSWQIATLLTFLTGLIEILMGVFRLGFL 184
            ||:.|:|||:|..:|:|:||.:|||||.:||...........|.||.||:|.|::.||:..||||
  Rat    64 LYSAFMGCFVYFVLGTSRDVTLGPTAIMSLLVSYYTFREPAYAVLLAFLSGCIQLAMGLLHLGFL 128

  Fly   185 IDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKT-SGNTFLQVWISIVNDIHNISWPDFILGIVCI 248
            :||:|.||..|||||.|:.|...|:|:.||::. ....||||:.:.:: |......|.|||:||:
  Rat   129 LDFISCPVIKGFTSAASITIGFGQVKNLLGLQNIPRQFFLQVYHTFLH-IGETRVGDAILGLVCM 192

  Fly   249 TLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNGKENLVKTV 313
            .|||.|:.:......|........|...|:.||:.||||||:|...|.:.|...|.|....:.|
  Rat   193 VLLLVLKLMREHIPPPHPEMPLGVKFSRGLVWTVTTARNALVVSFAALIAYAFEVTGSHPFILT- 256

  Fly   314 GFVPKGLPSFQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFA 378
            |.:.:|||..:.|||.: ...|:|.        ||.:||..:|.||.||||:.||||:||.::||
  Rat   257 GKIAQGLPPVRMPPFSV-TTDNKTI--------SFSEMVQDMGVGLAVVPLMGLLETIAVAKSFA 312

  Fly   379 --DGKPTDATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLY 441
              :....||.|||:|.|:.||..|.|......|...|.|:...:||.|....|.|.|:|:::|.|
  Rat   313 SQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGVLVLLSLDY 377

  Fly   442 LTPCFYYIPKAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIG 506
            ||..||||||:|||::||.||..:...::.:.:|..::.||:| |...|......:|.|||.|..
  Rat   378 LTLLFYYIPKSALAAVIIMAVAPLFDVKIFRRLWLVQRLDLLP-LCVTFLLSFWEIQYGILAGTL 441

  Fly   507 INVVFILYQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVRKVINKQGQKSTLP--VVID 569
            ::::.:|:..||||.::     :.| :.|:|.|...|.||:::.:|:.:.|:..:::.|  .|::
  Rat   442 VSLLILLHSVARPKTQV-----SEG-QILVLQPASGLHFPAVDALREAMTKRALEASPPRSAVLE 500

  Fly   570 CTHIYGADFTAAKVISTMVMDFKLREQPLFFYNLQPRVAQVFEGLNKDLVVIYDINTLHAKLAEK 634
            |||:...|:|....:..::.||:.:...|.|..||..|.:..  |..||.......||..  |||
  Rat   501 CTHVSNIDYTVILGLGELLEDFQKKGVTLAFVGLQVPVLRTL--LAADLKGFQYFTTLEE--AEK 561

  Fly   635 S 635
            |
  Rat   562 S 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	211/537 (39%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	22/79 (28%)
Slc26a11	XP_038943458.1	sulP	18..542	CDD:273284	212/541 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335189
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860