DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9717 and Slc26a11

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_006533481.1	Gene:	Slc26a11 / 268512	MGIID:	2444589	Length:	610	Species:	Mus musculus

Alignment Length:	596	Identity:	225/596 - (37%)
Similarity:	328/596 - (55%)	Gaps:	42/596 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PDESCLEGTQSCCSNLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAY 108
            || :|      |||        ...|.:|.|:|.|:|.|...::..|.:||:||.||||||||||
Mouse    20 PD-TC------CCS--------ATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLTVIPQALAY 69

  Fly   109 AGIAGLDLQYGLYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQIAGGSWQIATLLTFLTGLIE 173
            |.:|||..|||||:.|:|||:|.|:|:|:||.:|||||.:||...........|.||.||:|.|:
Mouse    70 AEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQ 134

  Fly   174 ILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGI-KTSGNTFLQVWISIVNDIHNIS 237
            :.||:..||||:||:|.||..|||||.|:.|...|:|:.||: |.....||||:.:.:: |....
Mouse   135 LAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVYHTFLH-IGETR 198

  Fly   238 WPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLF 302
            ..|.:||:..:.|||.|:.:......|......|.|...|:.||:.||||||:|...|.:.|...
Mouse   199 VGDAVLGLASMLLLLVLKCMREHMPPPHPEMPLAVKFSRGLVWTVTTARNALVVSSAALIAYAFE 263

  Fly   303 VNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIAL 367
            |.|....|.| |.:.:|||..:.|||.:.. .|:|.        ||.:||..:|:||.||||:.|
Mouse   264 VTGSHPFVLT-GKIAEGLPPVRIPPFSVTR-DNKTI--------SFSEMVQDMGAGLAVVPLMGL 318

  Fly   368 LETMAVVQAFA--DGKPTDATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLY 430
            ||::||.::||  :....||.|||:|.|:.||..|.|......|...|.|:...:||.|....|.
Mouse   319 LESIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLV 383

  Fly   431 TSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFFACLVL 495
            |..:|:::|.|||..|.||||:|||::||.||..:...::.:.:|..::.||:| |...|.....
Mouse   384 TGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFDVKIFRSLWRVQRLDLLP-LCVTFLLSFW 447

  Fly   496 PLQLGILVGIGINVVFILYQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVRKVINKQGQ 560
            .:|.|||.|..::::.:|:..||||.::     :.| :..:|.|...|.||:::.:|:.|..:..
Mouse   448 EIQYGILAGSLVSLLILLHSVARPKTQV-----SEG-QIFVLQPASGLYFPAIDALREAITNRAL 506

  Fly   561 KSTLP--VVIDCTHIYGADFTAAKVISTMVMDFKLREQPLFFYNLQPRVAQVFEGLNKDLVVIYD 623
            :::.|  .|::||||...|:|....:..::.||:.:...|.|..||..|.:..  |..||.....
Mouse   507 EASPPRSAVLECTHISSVDYTVIVGLGELLEDFQKKGVALAFVGLQVPVLRTL--LAADLKGFRY 569

  Fly   624 INTLHAKLAEK 634
            ..||..  |||
Mouse   570 FTTLEE--AEK 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	208/537 (39%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	22/79 (28%)
Slc26a11	XP_006533481.1	sulP	35..559	CDD:273284	209/541 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.710