DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9717 and Slc26a7

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_006537785.1	Gene:	Slc26a7 / 208890	MGIID:	2384791	Length:	692	Species:	Mus musculus

Alignment Length:	722	Identity:	153/722 - (21%)
Similarity:	284/722 - (39%)	Gaps:	208/722 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 SNLWSNIFR------KKTLYKRFPILVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIAGL 114
            |.||..:..      |:...:|.|||.|.|||. |:.:..|.|:||.:|:..:.|.|::|.::.:
Mouse    10 SVLWGKMHTPHREDIKQWCKRRLPILEWAPQYNLKENLLPDTVSGIMLAVQQVAQGLSFAMLSSV 74

  Fly   115 DLQYGLYACFLGCFIYIFIGSSKDVPIGPTAISALLS---------------------------- 151
            ...:|||.......||...|..:.|..|..|:::|:|
Mouse    75 HPVFGLYGSLFPAIIYAIFGMGRHVATGTFALTSLISANAVERLVPQSSRNLTTQSNSSVLGLSE 139

  Fly   152 --FQIAGGSWQIATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLG 214
              .|..|    :|..::||.|:|:::|.|.:||.....::.||.:..|:..:..:.:||:|..||
Mouse   140 FELQRIG----VAAAVSFLGGVIQLVMFVLQLGSATFLLTEPVISAMTTGAATHVVTSQVKYLLG 200

  Fly   215 IK---TSGNT-FLQVWISIVNDIHNISWPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQKLL 275
            ||   .||.. |..::..:..:|.::.....:..::.|.:|:.::.|       .|......|::
Mouse   201 IKMPYISGPLGFFYIYAYVFENIKSVQLEALLFSLLSIIVLVLVKEL-------NEQFKRKIKVV 258

  Fly   276 TGIFWTIGTARNALLVC----GTAGLGYWLFVNGKENLVKTVGFVPKGLPSFQPPPFH-MDAVVN 335
            ..:...:..|.:....|    .|.||             :.||.:|.|:|..:.||.: :.||:.
Mouse   259 LPVDLVLIIAASFACYCTNMENTYGL-------------EVVGHIPNGIPPPRAPPMNILSAVLT 310

  Fly   336 ETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFAD--GKPTDATQELIASGVCNVA 398
            |..|                      |.|:..:.::|:.|..|.  ....|..||.:|.|:.||.
Mouse   311 EAFG----------------------VALVGYVASLALAQGSAKKFKYSVDDNQEFLAHGLSNVI 353

  Fly   399 NSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVI 463
            .||:..:.|...:.|.|.|.::|.:||::.|.:.:.|:|.:..:.|..|::|...|||||:..:.
Mouse   354 PSFLFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLK 418

  Fly   464 -FMVQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPK------- 520
             .::|:|.:|..|:..|.|....:..:...:.....:|:|.|:...:..:|.:..|.|
Mouse   419 GMLIQFRDLKKYWNVDKIDWGIWISTYIFTICFAANVGLLFGVICTIAIVLGRFPRAKTLSITDM 483

  Fly   521 ----LRIET-----------------------LATTTGLKYLMLTPDRC--------------LI 544
                |:::|                       |.|.:.::.|.:||.|.              |:
Mouse   484 KEMELKVKTEMHDSTENWPPSKRTNVKVFPGSLKTGSNIRSLSVTPRRMETSQQIKIISINNPLV 548

  Fly   545 F-PSMEF---VRKVINKQG------------QKSTL----------------------PVVIDCT 571
            | .:.:|   :.|:|.|:.            :::||                      .:|::|:
Mouse   549 FLNAKKFSADLMKIILKESDSNQPLDDVSKCEQNTLLSSLSNGNCNEEASQPCSSEKCSLVLNCS 613

  Fly   572 HIYGADFTAAKVISTMVMDFKLR-------------------------EQPLFFYNLQPRVAQVF 611
            .:...|:|....:..:.:|.|.|                         |:|:||.:: |....:.
Mouse   614 GLTFFDYTGVSTLVELYLDCKSRSVDVFLANCTASLIKAMTYYGDLDTEKPIFFDSV-PAAISII 677

  Fly   612 EGLNKDL 618
            :. ||:|
Mouse   678 QS-NKNL 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	145/686 (21%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	24/154 (16%)
Slc26a7	XP_006537785.1	Sulfate_transp	47..444	CDD:366367	103/442 (23%)
Slc26a7	XP_006537785.1	STAS_SulP_like_sulfate_transporter	533..668	CDD:132913	18/134 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810